ArticleNutrition research and practice2016
Elevation of heart-femoral pulse wave velocity by short-term low sodium diet followed by high sodium diet in hypertensive patients with sodium sensitivity.
Article in Nutrition research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.
- Current Data on Dietary Sodium, Arterial Structure and Function in Humans: A Systematic Review.Nutrients · 2019Pooled it
- More evidence that salt increases blood pressure and risk of kidney disease from the Science of Salt: A regularly updated systematic review of salt and health outcomes (April-July 2016).Journal of clinical hypertension (Greenwich, Conn.) · 2017Pooled it
- Short-term high sodium intake increases nocturnal blood pressure but not arterial stiffness in Black adults.European journal of nutrition · 2026Article
- Etiological Diagnosis and Personalized Therapy for Hypertension: A Hypothesis of the REASOH Classification.Journal of personalized medicine · 2023Review
- Association of urinary sodium/potassium ratio with structural and functional vascular changes in non-diabetic hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Antihypertensive effect of Ganjang (traditional Korean soy sauce) on Sprague-Dawley Rats.Nutrition research and practice · 2017Article
- Relationship between 24-h urine sodium/potassium ratio and central aortic systolic blood pressure in hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesWe compared changes in heart-femoral pulse wave velocity (hfPWV) in response to low sodium and high sodium diet between individuals with sodium sensitivity (SS) and resistance (SR) to evaluate the influence of sodium intake on arterial stiffness. SUBJECTS/
methodsThirty-one hypertensive and 70 normotensive individuals were given 7 days of low sodium dietary approach to stop hypertension (DASH) diet (LSD, 100 mmol NaCl/day) followed by 7 days of high sodium DASH diet (HSD, 300 mmol NaCl/day) during 2 weeks of hospitalization. The hfPWV was measured and compared after the LSD and HSD.
resultsThe hfPWV was significantly elevated from LSD to HSD in individuals with SS (P = 0.001) independently of changes in mean arterial pressure (P = 0.037). Conversely, there was no significant elevation of hfPWV from LSD to HSD in individuals with SR. The percent change in hfPWV from the LSD to the HSD in individuals with SS was higher than that in individuals with SR. Subgroup analysis revealed that individuals with both SS and hypertension showed significant elevation of hfPWV from LSD to HSD upon adjusted analysis using changes of the means arterial pressure (P = 0.040). However, there was no significant elevation of hfPWV in individuals with SS and normotension.
conclusionHigh sodium intake elevated hfPWV in hypertensive individuals with SS, suggesting that high sodium intake increases aortic stiffness, and may contribute to enhanced cardiovascular risk in hypertensive individuals with SS.
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