Evidence map›Paper›PMID 27247714›Full record

ReviewWorld journal of radiology2016

Review of renal cell carcinoma and its common subtypes in radiology.

Gavin Low, Guan Huang, Winnie Fu, Zaahir Moloo, Safwat Girgis

Abstract readReview
In one paragraph

Review in World journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Application of BOLDZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
    Trial
  6. Review
  7. Article
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  9. Solid masses arising in transplanted kidneys.Abdominal radiology (New York) · 2026
    Review
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gavin LowGavin Low, Guan Huang, Winnie Fu, Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton, Alberta T6G 2B7, Canada.
Guan HuangGavin Low, Guan Huang, Winnie Fu, Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton, Alberta T6G 2B7, Canada.
Winnie FuGavin Low, Guan Huang, Winnie Fu, Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton, Alberta T6G 2B7, Canada.
Zaahir MolooGavin Low, Guan Huang, Winnie Fu, Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton, Alberta T6G 2B7, Canada.
Safwat GirgisGavin Low, Guan Huang, Winnie Fu, Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton, Alberta T6G 2B7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Representing 2%-3% of adult cancers, renal cell carcinoma (RCC) accounts for 90% of renal malignancies and is the most lethal neoplasm of the urologic system. Over the last 65 years, the incidence of RCC has increased at a rate of 2% per year. The increased incidence is at least partly due to improved tumor detection secondary to greater availability of high-resolution cross-sectional imaging modalities over the last few decades. Most RCCs are asymptomatic at discovery and are detected as unexpected findings on imaging performed for unrelated clinical indications. The 2004 World Health Organization Classification of adult renal tumors stratifies RCC into several distinct histologic subtypes of which clear cell, papillary and chromophobe tumors account for 70%, 10%-15%, and 5%, respectively. Knowledge of the RCC subtype is important because the various subtypes are associated with different biologic behavior, prognosis and treatment options. Furthermore, the common RCC subtypes can often be discriminated non-invasively based on gross morphologic imaging appearances, signal intensity on T2-weighted magnetic resonance images, and the degree of tumor enhancement on dynamic contrast-enhanced computed tomography or magnetic resonance imaging examinations. In this article, we review the incidence and survival data, risk factors, clinical and biochemical findings, imaging findings, staging, differential diagnosis, management options and post-treatment follow-up of RCC, with attention focused on the common subtypes.

Indexed as

Chromophobe renal cell carcinomaClear cell renal cell carcinomaMagnetic resonance imagingMultidetector computed tomographyPapillary renal cell carcinomaTreatment protocolsTumor staging

Identifiers

PMID27247714
PMCPMC4882405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.