ArticlePsychiatry investigation2016
Systemic Family Therapy of Comorbidity of Anxiety and Depression with Epilepsy in Adolescents.
Article in Psychiatry investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 7 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 7 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Efficacy of psychological and behavioral interventions for depressive symptoms in people with epilepsy: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Service delivery, behavioural, and self-management interventions for children with epilepsy.The Cochrane database of systematic reviews · 2025Pooled it
- Service delivery, behavioural, and self-management interventions for adults with epilepsy.The Cochrane database of systematic reviews · 2025Pooled it
- Systematic review and meta-analysis of the effect of psychological interventions on anxiety in children and youth with chronic medical conditions.Journal of pediatric psychology · 2025Pooled it
- Systematic review and meta-analysis of psychological interventions for depression symptoms in young people with long-term physical health conditions.Journal of pediatric psychology · 2025Pooled it
- Psychological therapies for anxiety and depression in children and adolescents with long-term physical conditions.The Cochrane database of systematic reviews · 2018Pooled it
- Psychological treatments for people with epilepsy.The Cochrane database of systematic reviews · 2017Pooled it
- An intensive education program for caregivers ameliorates anxiety, depression, and quality of life in patients with drug-resistant temporal lobe epilepsy and mesial temporal sclerosis who underwent cortico-amygdalohippocampectomy.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Trial
- Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study.BMC research notes · 2025Article
- Association Between Family Atmosphere and Internet Addiction Among Adolescents: The Mediating Role of Self-Esteem and Negative Emotions.International journal of public health · 2023Article
- Prediction of Chinese clients' satisfaction with psychotherapy by machine learning.Frontiers in psychiatry · 2023Article
- Childhood maltreatment and suicide ideation: A possible mediation of social support.World journal of psychiatry · 2022Article
- A study on the correlation between family dynamic factors and depression in adolescents.Frontiers in psychiatry · 2022Article
- The Quality of Life and Its Relationship With Systemic Family Dynamics and Mental Health in Senior High School Students From Shaanxi, China.Frontiers in public health · 2022Observational
- Development of a measure quantifying helpful psychotherapy interventions: The Helpful Therapeutic Attitudes and Interventions Scale.Frontiers in psychiatry · 2022Article
- The Relationship Between Mental Health Problems and Systemic Family Dynamics Among High School and University Students in Shaanxi Province, China.International journal of public health · 2021Article
- Clinical Study on Electronic Medical Neuroelectric Stimulation Based on the Internet of Things to Treat Epilepsy Patients with Anxiety and Depression.Journal of healthcare engineering · 2021Article
- Psychological treatments for people with epilepsy.The Cochrane database of systematic reviews · 2020Review
- Clinical characteristics of moderate-severe obsessive-compulsive disorder in children and adolescents in China.The Journal of international medical research · 2020Article
- What Do Chinese Families With Depressed Adolescents Find Helpful in Family Therapy? A Qualitative Study.Frontiers in psychology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to find if systemic family therapy (SFT) does work in anxiety and depression with epilepsy in adolescents (ADAE).
methods104 adolescents with epilepsy, aged 13-20 years old, were included from December 2009 to December 2010, the enrolled patients were with anxiety [Hamilton Anxiety Scale (HAMA) score ≥14 points] or depression [Hamilton Depression Scale (HAMD) score ≥20 points]. The patients were randomly divided into the control group (n=52) treated with antiepileptic drugs (AED) and the intervention group (n=52) undergone Systemic Family Therapy (SFT) as well as AED. The AED improvements, anxiety and depression scores, Social Support Rating Scale (SSRS), Family Assessment Device (FAD) and scale of systemic family dynamics (SSFD) were observed after 3-month treatment.
resultsThe frequencies of epileptic seizures in intervention group was decreased much more significantly than the control group (4.22±3.54 times/month vs. 6.20±5.86 times/month, p=0.04); and the scores of anxiety (9.52±6.28 points vs. 13.48±8.47 points, p=0.01) and depression (13.86±9.17 points vs. 18.89±8.73 points, p=0.02) were significantly decreased than the control group; meanwhile, the family dynamics and family functions were significantly improved, and the social support was also increased (p<0.05).
conclusionSFT combined with AEDs had better efficacies than AEDs alone, not only the frequency of epileptic seizures was decreased, but also the patients' anxiety and depression were improved, and the family dynamics, family functions and social support were improved.
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