Evidence map›Paper›PMID 27247462›Full record

Trial reportThe Canadian veterinary journal = La revue veterinaire canadienne2016

Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease.

Alfonso Lopez-Rodriguez, Jeroen Dewulf, Tom Meyns, Rubén Del-Pozo-Sacristán, Christine Andreoni, Anne Goubier, Ludivine Chapat, Catherine Charreyre, François Joisel, Dominiek Maes

Abstract readClinical Trial
In one paragraph

Trial report in The Canadian veterinary journal = La revue veterinaire canadienne, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Speculative Review on the Feasibility of Porcine Circovirus 2 Elimination.Animals : an open access journal from MDPI · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Effect ofPorcine health management · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alfonso Lopez-RodriguezFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Jeroen DewulfFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Tom MeynsFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Rubén Del-Pozo-SacristánFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Christine AndreoniFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Anne GoubierFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Ludivine ChapatFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Catherine CharreyreFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
François JoiselFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Dominiek MaesFaculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).
Ghent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated porcine circovirus type 2 (PCV2) virological profiles in herds affected (PCVAD-AH, n = 5) or non-affected (PCVAD-NAH, n = 4) by PCV2-associated diseases (PCVAD), before and after 1 y of PCV2 gilt and sow vaccination. Fresh feces from the floor (5 pens/age/farm) and 5 blood samples (1/pen) were collected at 3, 9, 15, 21 wk. Individual feces and blood samples were collected from 5 gilts and 15 sows. Sampling was repeated 1 y after vaccination. Quantitative PCR on feces, PCV2 antibodies in blood serum and cell-mediated immunity were investigated. Before vaccination, pigs of PCVAD-AH had higher viral load in feces (9 and 15 wk), lower IgG and higher IgM (3 wk) and lower lymphocyte counts (9 and 15 wk) suggesting immunosuppression. Vaccination reduced viral load in growers, increased IgG (3 wk) suggesting improved maternal immunity, reduced IgM (3 wk), increased total antibody titers in sows and increased CD79a cells in the pigs.

Indexed as

CircovirusAnimalsCD79 AntigensCircoviridae InfectionsFecesFemaleImmunity, CellularReal-Time Polymerase Chain ReactionSwineSwine DiseasesViral VaccinesCD79 AntigensViral Vaccines

Identifiers

PMID27247462
PMCPMC4866667
OpenAlexW2416680052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.