Evidence map›Paper›PMID 27247235›Full record

ArticleVascular medicine (London, England)2016

Endovascular therapy for advanced post-thrombotic syndrome: Proceedings from a multidisciplinary consensus panel.

Suresh Vedantham, Susan R Kahn, Samuel Z Goldhaber, Anthony J Comerota, Sameer Parpia, Sreelatha Meleth, Diane Earp, Rick Williams, Akhilesh K Sista, William Marston and 5 more

Open access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Vascular medicine (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Angioplasty or stenting for deep venous thrombosis.The Cochrane database of systematic reviews · 2025
    Pooled it
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  8. Review
  9. Article
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  11. Article
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  13. Article
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  16. Thrombectomy and thrombolysis for the prevention and treatment of postthrombotic syndrome.Hematology. American Society of Hematology. Education Program · 2017
    Review
  17. Review
  18. Knowns and Unknowns in Managing Postthrombotic Syndrome.Seminars in interventional radiology · 2017
    Review
  19. Review
  20. The post-thrombotic syndrome.Hematology. American Society of Hematology. Education Program · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 2 countries.

Suresh VedanthamWashington University in St Louis, St Louis, MO, USA vedanthams@mir.wustl.edu.
Susan R KahnSMBD Jewish General Hospital, Montreal, QC, Canada.
Samuel Z GoldhaberBrigham and Womens Hospital, Boston, MA, USA.
Anthony J ComerotaThe Toledo Hospital, Toledo, OH, USA.
Sameer ParpiaMcMaster University, Hamilton, ON, Canada.
Sreelatha MelethResearch Triangle International, Research Triangle Park, NC, USA.
Diane EarpResearch Triangle International, Research Triangle Park, NC, USA.
Rick WilliamsResearch Triangle International, Research Triangle Park, NC, USA.
Akhilesh K SistaNew York University School of Medicine, New York, NY, USA.
William MarstonUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Suman RathbunOK Health Sciences Center, Oklahoma City, OK, USA.
Elizabeth A MagnusonMid America Heart Institute, Kansas City, MO, USA.
Mahmood K RazaviSt Joseph's Hospital, Orange, CA, USA.
Michael R JaffMassachusetts General Hospital, Boston, MA, USA.
Clive KearonMcMaster University, Hamilton, ON, Canada.
RTI International · USMcMaster University · CABrigham and Women's Hospital · USJewish General Hospital · CAMassachusetts General Hospital · USNew York University · USProMedica Toledo Hospital · USSt. Joseph's Hospital · USUniversity of North Carolina at Chapel Hill · USUniversity of Oklahoma Health Sciences Center · USWashington University in St. Louis · US

Funding

Clinical Trials Development Resource for Hematologic Disorders (U24)U24HL114577 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI CATELLIER, DIANE J · 2012 to 2016
$3.2M
CHRONIC VENOUS THROMBOSIS: RELIEF WITH ADJUNCTIVE CATHETER-BASED THERAPY (C-TRACTU34HL123831 · NHLBI · WASHINGTON UNIVERSITY · PI VEDANTHAM, SURESH · 2014 to 2015
$654k
NHLBI NIH HHS U24 HL114577NHLBI NIH HHS U34 HL123831
6 · The paper itself

Abstract

Patients with advanced post-thrombotic syndrome (PTS) and chronic iliac vein obstruction suffer major physical limitations and impairment of health-related quality of life. Currently there is a lack of evidence-based treatment options for these patients. Early studies suggest that imaging-guided, catheter-based endovascular therapy can eliminate iliac vein obstruction and saphenous venous valvular reflux, resulting in reduced PTS severity; however, these observations have not been rigorously validated. A multidisciplinary expert panel meeting was convened to plan a multicenter randomized controlled clinical trial to evaluate endovascular therapy for the treatment of advanced PTS. This article summarizes the findings of the panel, and is expected to assist in developing a National Institutes of Health-sponsored clinical trial and other studies to improve the care of patients with advanced PTS.

Indexed as

Endovascular ProceduresResearch DesignConsensusHumansMulticenter Studies as TopicPostthrombotic SyndromeRandomized Controlled Trials as Topicdeep vein thrombosisendovascular therapypost-thrombotic syndromequality of lifestent

Identifiers

PMID27247235
PMCPMC4963268
OpenAlexW2412503186

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.