ArticleBMJ case reports2016
Stroke and a valvular lesion in a patient with stage IV non-small cell lung cancer.
Article in BMJ case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Non-bacterial Thrombotic Endocarditis in Lung Cancer: A Systematic Review.Current cardiology reviews · 2025Pooled it
- Clinical insights into nonbacterial thrombotic endocarditis in cancer patients: A case-based systematic review.ARYA atherosclerosis · 2025Review
- Trivalvular nonbacterial thrombotic endocarditis in a patient with colon adenocarcinoma: a case report.Journal of medical case reports · 2023Article
- Review
- When Two Maladies Meet: Disease Burden and Pathophysiology of Stroke in Cancer.International journal of molecular sciences · 2022Review
- Mesothelioma with Nonbacterial Thrombotic Endocarditis: A Case Report.JNMA; journal of the Nepal Medical Association · 2021Article
- Cancer-Related Non-Bacterial Thrombotic Endocarditis Presenting as Acute Ischemic Stroke.Cureus · 2021Article
- Nonbacterial thrombotic endocarditis in a patient with primary antiphospholipid syndrome.Oxford medical case reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanism and severity of stroke varies in the setting of malignancy. We report a case of a 68-year-old man with lung adenocarcinoma, who experienced acute neurological symptoms. Imaging studies showed multiple acute ischaemic infarcts in cerebral and cerebellar hemispheres. Further work up was consistent with non-bacterial thrombotic endocarditis (NBTE). We highlight, through a review of the literature, the importance of transoesophageal echocardiography (TOE) in defining the above diagnosis. The treatment of NBTE consists of systemic anticoagulation and therapy of the underlying malignancy. Enoxaparin is preferred over warfarin to achieve this goal. He received systemic targeted therapy with erlotinib. A TOE performed 8 months later showed complete resolution of the vegetation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.