ArticleThe Onderstepoort journal of veterinary research2016
Cryptosporidium genotypes in children and calves living at the wildlife or livestock interface of the Kruger National Park, South Africa.
Article in The Onderstepoort journal of veterinary research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Cryptosporidium infections in terrestrial ungulates with focus on livestock: a systematic review and meta-analysis.Parasites & vectors · 2019Pooled it
- A review of wildlife tourism and meta-analysis of parasitism in Africa's national parks and game reserves.Parasitology research · 2018Pooled it
- Point-of-Care Diagnosis of Cryptosporidiosis in Neonatal Ruminant Faecal Samples by a Portable Field Microscope Integrated With a Smartphone.Veterinary medicine and science · 2025Article
- Genetic diversity ofCurrent research in parasitology & vector-borne diseases · 2025Article
- Review
- Prevalence and associated risk factors of Cryptosporidium infection in calves and hospitalized humans in Libo Kemkem, North Western Ethiopia.Veterinary medicine and science · 2024Article
- Molecular characterization and zoonotic risk assessment ofOne health (Amsterdam, Netherlands) · 2024Article
- Population genetics of Cryptosporidium parvum subtypes in cattle in Poland: the geographical change of strain prevalence and circulation over time.BMC veterinary research · 2022Article
- Sparse Evidence forPathogens (Basel, Switzerland) · 2021Article
- Cryptosporidium Infection and Associated Risk Factors among Cattle in the Central Region of Ghana.Journal of parasitology research · 2021Article
- Rotavirus and Cryptosporidium pathogens as etiological proxies of gastroenteritis in some pastoral communities of the Amathole District Municipality, Eastern Cape, South Africa.BMC research notes · 2020Article
- Review
- Factors Associated WithFrontiers in public health · 2020Article
- Molecular characterization of Cryptosporidium spp. and Giardia duodenalis in children in Egypt.Parasites & vectors · 2018Article
- Review
- Cryptosporidium and Giardia in Africa: current and future challenges.Parasites & vectors · 2017Review
- Prevalence and risk factors of Cryptosporidium infection in farmed pigs in Zhejiang, Guangdong, and Yunnan provinces, China.Tropical animal health and production · 2017Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cryptosporidium infection is one of the most common causes of parasitic diarrhoea worldwide in cattle and humans. In developing countries, human cryptosporidiosis is most prevalent during early childhood and links between zoonotic infection and animal related activities have been demonstrated. This study investigated the prevalence and species/genotype distribution of Cryptosporidium among children (< 5 years) and calves (< 6 months) living in a rural farming area adjacent to the Kruger National Park in South Africa, where interactions between humans and wild and domestic animals are known to occur. Cryptosporidium oocysts were detected in 8/143 stool samples of children recruited within the hospital system (5.6%; 95% CI 2.4%, 10.7%) and in 2/352 faecal samples of calves (0.6%; 95% CI 0.1%, 2.0%) using the modified Ziehl-Neelsen (MZN) staining technique. Microscopy positive samples from children were further analysed by PCR targeting the 18S rRNA gene and identified as Cryptosporidium hominis (3/4) and Cryptosporidium meleagridis (1/4). Regardless of the microscopy outcome, randomly selected samples (n = 36) from calves 0-4 months of age were amplified and sequenced at the 18S rRNA gene using nested PCR. Two calves tested positive (5.6%; 95% CI 1.7%, 18.7%), and revealed the presence of Cryptosporidium parvum and Cryptosporidium bovis. The detection of only two zoonotic species (C. parvum in one calf and C. meleagridis in one child) suggests that zoonotic cryptosporidiosis is not currently widespread in our study area; however, the potential exists for amplification of transmission in an immunocompromised population.
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Registered trials
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