Evidence map›Paper›PMID 27246780›Full record

ArticleAntimicrobial agents and chemotherapy2016

Extensive Shared Chemosensitivity between Malaria and Babesiosis Blood-Stage Parasites.

Aditya S Paul, Cristina K Moreira, Brendan Elsworth, David R Allred, Manoj T Duraisingh

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Immunity beyond borders: non-lethalFrontiers in immunology · 2026
    Article
  2. The essential genome ofScience (New York, N.Y.) · 2025
    Article
  3. Comparative chemical genomics inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Review
  6. Pathogens and global health · 2023
    Article
  7. Article
  8. Treatment of Human Babesiosis: Then and Now.Pathogens (Basel, Switzerland) · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Establishment of a continuousThe Journal of biological chemistry · 2018
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aditya S PaulDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Cristina K MoreiraDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Brendan ElsworthDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
David R AllredDepartment of Infectious Diseases and Pathology, University of Florida, Gainesville, Florida, USA Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.
Manoj T DuraisinghDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA mduraisi@hsph.harvard.edu.
Harvard University · USUniversity of Florida · US

Funding

Functional analysis of erythrocyte determinants of malaria infectionR01AI091787 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI DURAISINGH, MANOJ T · 2011 to 2015
$2.0M
NIAID NIH HHS R01 AI091787
6 · The paper itself

Abstract

The apicomplexan parasites that cause malaria and babesiosis invade and proliferate within erythrocytes. To assess the potential for common antiparasitic treatments, we measured the sensitivities of multiple species of Plasmodium and Babesia parasites to the chemically diverse collection of antimalarial compounds in the Malaria Box library. We observed that these parasites share sensitivities to a large fraction of the same inhibitors and we identified compounds with strong babesiacidal activity.

Indexed as

AnimalsAntimalarialsBabesiaBabesiosisMalariaParasitesPlasmodiumAntimalarials

Identifiers

PMID27246780
PMCPMC4958166
OpenAlexW2413244229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.