ReviewEuropean respiratory review : an official journal of the European Respiratory Society2016
Malignant pleural effusion: from bench to bedside.
Review in European respiratory review : an official journal of the European Respiratory Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04039126 (Comparison of the Effectiveness of Povidone-Iodine Alone to Povidone-Iodine-Tetracycline Combination for Chemical Pleurodesis in Malignant Pleural Effusion), which is not on this map. Cited by 148 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of the Effectiveness of Povidone-Iodine Alone to Povidone-Iodine-Tetracycline Combination for Chemical Pleurodesis in Malignant Pleural Effusion
Who cites it
148 citing papers in PubMed, 4 syntheses or guidelines pooled it, 278 citations in OpenAlex.
- Performance of the Monoclonal Antibody B72.3 in Diagnosis of Malignant Carcinomatous Serous Effusions-A Systematic Review and Meta-Analysis of Diagnostic Performance.Cytopathology : official journal of the British Society for Clinical Cytology · 2025Pooled it
- Talc slurry versus thoracoscopic talc insufflation for malignant pleural effusion: a systematic review and meta-analysis.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024Pooled it
- Intrapleural Perfusion With Staphylococcal Enterotoxin C for Malignant Pleural Effusion: A Clustered Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Evaluation of efficacy and safety for Brucea javanica oil emulsion in the control of the malignant pleural effusions via thoracic perfusion.BMC cancer · 2018Pooled it
- Efficacy and safety profile of autologous blood versus talc pleurodesis for malignant pleural effusion: a randomized controlled trial.Therapeutic advances in respiratory diseaseTrial
- The RATAB Framework: An Interpretable AI-Driven Radiographic Risk Stratification Model for Suspected Lung Lesions.Journal of imaging informatics in medicine · 2026Article
- Risks of adverse respiratory outcomes in adults with cancer over the course of survivorship compared with cancer-free individuals: a matched cohort study using linked English electronic health records.EClinicalMedicine · 2026Article
- Clinical Utility of Pleural Tissue Debris Incidentally Obtained During Drainage of Pleural Effusion: A Retrospective Cohort Study.Biomedicines · 2026Article
- Qualitative insights into patient and carer perspectives of malignant pleural effusion management: an embedded study within the TACTIC trial.BMJ open respiratory research · 2026Article
- Contemporary Pleural Drainage in Adult Practice: Image-Guided Techniques, Procedural Safety, Training Standards, and Malignant Pleural Effusion Management.Journal of clinical medicine · 2026Review
- Ultrasonographic characterization of malignant pleural effusion in a murine experimental model.BMC cancer · 2026Article
- Pleural effusion volume as a novel biomarker for prognostic and therapeutic stratification in small cell lung cancer: a translationally-focused cohort study.Translational lung cancer research · 2026Article
- Comparison of LENT, PROMISE, and RECLS scores in malignant pleural effusions.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Affordable use of indwelling pleural catheters for malignant pleural effusion.Lung India : official organ of Indian Chest Society · 2026Article
- Timing of definitive pleural intervention within systemic anticancer therapy in malignant pleural effusion from high-response lung cancers: a retrospective single-center cohort study.Translational lung cancer research · 2026Article
- Pleural fluid C-C motif chemokine ligand 2 as a diagnostic biomarker for malignant pleural effusion.Journal of thoracic disease · 2026Article
- The utility of a pleural carcinomatosis score for assessing resectability.Pleura and peritoneum · 2026Article
- Recurrent Malignant Pleural Effusion Management: Evaluating Quality Gaps, Outcomes, Costs, and Adherence to Guideline-Consistent Care.CHEST pulmonary · 2026Article
- Article
- Pathobiology and clinical significance of malignant pleural effusions.EMBO molecular medicine · 2026Review
88 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
5 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant pleural effusion (MPE) is a common but serious condition that is related with poor quality of life, morbidity and mortality. Its incidence and associated healthcare costs are rising and its management remains palliative, with median survival ranging from 3 to 12 months. During the last decade there has been significant progress in unravelling the pathophysiology of MPE, as well as its diagnostics, imaging, and management. Nowadays, formerly bed-ridden patients are genotyped, phenotyped, and treated on an ambulatory basis. This article attempts to provide a comprehensive overview of current advances in MPE from bench to bedside. In addition, it highlights unanswered questions in current clinical practice and suggests future directions for basic and clinical research in the field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.