ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2016
Electrophysiological and histological changes of paraspinal muscles in adolescent idiopathic scoliosis.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between lean mass and adolescent idiopathic scoliosis: a meta-analysis.BMC musculoskeletal disorders · 2023Pooled it
- Association between ladybird homeobox 1 gene polymorphisms and adolescent idiopathic scoliosis: A MOOSE-compliant meta-analysis.Medicine · 2019Pooled it
- Integrated transcriptomic and functional analysis reveals tissue-specific molecular pathology in adolescent idiopathic scoliosis.HGG advances · 2026Article
- Pelvic Floor Muscle Activity in Adolescent Idiopathic Scoliosis.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Lumbar Muscle Morphology Correlates With Early Surgical Outcomes in Adolescent Idiopathic Scoliosis: A Pilot Study.Global spine journal · 2026Article
- Lumbar muscle morphology and composition in adolescent idiopathic scoliosis: a magnetic resonance study.Spine deformity · 2026Article
- Differential Activation of the Multifidus and Erector Spinae During Asymmetric Spinal Stabilizing Exercise in Adolescent Idiopathic Scoliosis.Annals of rehabilitation medicine · 2026Article
- Association Between Asymmetrical Muscle Activation and Three-Dimensional Spinal Deformity in Thoracic-Origin Idiopathic Scoliosis Assessed Using Surface Electromyography and EOS Imaging.Journal of clinical medicine · 2026Article
- The role of proprioception in the management and rehabilitation of adolescent idiopathic scoliosis.Frontiers in rehabilitation sciences · 2026Article
- Integrating intrinsic musculoskeletal pathology and genetics: Recent advances in unravelling the causative factors of adolescent idiopathic scoliosis.Bone reports · 2025Review
- Whole genome sequencing in adolescent idiopathic scoliosis cohort implicates multiple biological pathways.NPJ genomic medicine · 2025Article
- Asymmetric Degenerative Changes Between Convex and Concave Sides in Symptomatic Adult Degenerative Scoliosis.Journal of clinical medicine · 2025Article
- Evaluation of paraspinal muscles in adolescent idiopathic scoliosis: a study based on shear wave elastography.Spine deformity · 2025Article
- The Neurogenic Abnormities of Paraspinal Muscles Lead to Asymmetry of Fibre Types in Adolescent Idiopathic Scoliosis.Journal of cellular and molecular medicine · 2025Article
- Distinct clinical characteristics of adolescent idiopathic scoliosis with asymmetrical ESR1 expression in paraspinal muscle progenitor cells.JOR spine · 2024Article
- The role of the paraspinal muscles in the development of adolescent idiopathic scoliosis based on surface electromyography and radiographic analysis.BMC musculoskeletal disorders · 2024Article
- The Improvement of Trunk Muscle Endurance in Adolescents with Idiopathic Scoliosis Treated with ScoliBraceJournal of clinical medicine · 2024Article
- The alteration of LBX1 expression is associated with changes in parameters related to energy metabolism in mice.PloS one · 2024Article
- Adolescent idiopathic scoliosis is associated with muscle area asymmetries in the lumbar spine.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Electromyographic Discrepancy in Paravertebral Muscle Activity Predicts Early Curve Progression of Untreated Adolescent Idiopathic Scoliosis.Asian spine journal · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe pathogenesis of adolescent idiopathic scoliosis (AIS) remains poorly understood. To date, potentially involved local changes in the deep paraspinal muscles still remain unknown.
methodsNeedle electromyography (EMG) and muscle biopsy of paraspinal muscles at convexity and concavity of the AIS main thoracic curve were performed in 25 subjects. In this group, EMG was performed in 16 AIS subjects (12 females, 12-27 years), muscle biopsy in 18 AIS subjects (15 females, 11-31 years) compared to 10 non-scoliotic controls (6 females, 12-55 years). Samples of muscle tissue were removed during corrective surgery and were examined histologically, enzyme histochemically and immunohistochemically. Both methods of EMG and muscle biopsy were performed in 9 subjects (7 women, 12-27 years).
resultsRight curve convexity was found in 24 AIS subjects. Amplitudes of motor unit action potentials (MUPs) were significantly increased on the AIS curve convexity versus concavity. Turns, duration and phases of MUPs were without any significant changes. In all 18 subjects, the histological examination revealed muscle fiber redistribution with numerical predominance of type I on the curve convexity which strongly correlated with the progression of the Cobb angle.
conclusionOur findings demonstrate significant changes of muscle fiber redistribution in the paraspinal muscles of AIS with increased proportion of type I on the convexity corresponding to a significantly higher amplitude of MUPs on the same side. A possible explanation of this alteration is a secondary adaptation due to chronic high load demand.
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