Evidence map›Paper›PMID 27245843›Full record

SynthesisBMC geriatrics2016

Systems to identify potentially inappropriate prescribing in people with advanced dementia: a systematic review.

Domenica Disalvo, Tim Luckett, Meera Agar, Alexandra Bennett, Patricia Mary Davidson

Abstract readSystematic Review
In one paragraph

Synthesis in BMC geriatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Methodological evaluation of the psychometric properties of medication-related quality indicators in residential aged care homes: a systematic review.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2026
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  5. Carers' experiences and perspectives of the use of anticholinergic medications in people living with dementia: Analysis of an online discussion forum.Health expectations : an international journal of public participation in health care and health policy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Domenica DisalvoCentre for Cardiovascular and Chronic Care, Faculty of Health, University of Technology Sydney (UTS), 235-253 Jones St, Ultimo, NSW, 2007, Australia. domenica.m.disalvo@student.uts.edu.au.
Tim LuckettCentre for Cardiovascular and Chronic Care, Faculty of Health, University of Technology Sydney (UTS), 235-253 Jones St, Ultimo, NSW, 2007, Australia.
Meera AgarCentre for Cardiovascular and Chronic Care, Faculty of Health, University of Technology Sydney (UTS), 235-253 Jones St, Ultimo, NSW, 2007, Australia.
Alexandra BennettNSW Therapeutic Advisory Group, Sydney, NSW, Australia.
Patricia Mary DavidsonSt Vincent's Hospital, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystems for identifying potentially inappropriate medications in older adults are not immediately transferrable to advanced dementia, where the management goal is palliation. The aim of the systematic review was to identify and synthesise published systems and make recommendations for identifying potentially inappropriate prescribing in advanced dementia.

methodsStudies were included if published in a peer-reviewed English language journal and concerned with identifying the appropriateness or otherwise of medications in advanced dementia or dementia and palliative care. The quality of each study was rated using the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) checklist. Synthesis was narrative due to heterogeneity among designs and measures. Medline (OVID), CINAHL, the Cochrane Database of Systematic Reviews (2005 - August 2014) and AMED were searched in October 2014. Reference lists of relevant reviews and included articles were searched manually.

resultsEight studies were included, all of which were scored a high quality using the STROBE checklist. Five studies used the same system developed by the Palliative Excellence in Alzheimer Care Efforts (PEACE) Program. One study used number of medications as an index, and two studies surveyed health professionals' opinions on appropriateness of specific medications in different clinical scenarios.

conclusionsFuture research is needed to develop and validate systems with clinical utility for improving safety and quality of prescribing in advanced dementia. Systems should account for individual clinical context and distinguish between deprescribing and initiation of medications.

Indexed as

DementiaDrug PrescriptionsInappropriate PrescribingMedication Therapy ManagementAgedChecklistHumansObservational Studies as TopicPotentially Inappropriate Medication ListQuality ImprovementDementiaDeprescribingInappropriate prescribingMedication reviewPalliative carePolypharmacy

Identifiers

PMID27245843
PMCPMC4888427

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.