ReviewJournal of cardiovascular translational research2016
Old Myths, New Concerns: the Long-Term Effects of Ascending Aorta Replacement with Dacron Grafts. Not All That Glitters Is Gold.
Review in Journal of cardiovascular translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 108 citations in OpenAlex.
- Generation of Fibrin-Based Aortic Vessels with Layer-Specific Cell Architecture Under Pulsatile Perfusion in a Clinical Organ Care System.Annals of biomedical engineering · 2026Article
- From Case Studies to Cohort of Patients: Automating FSI Simulations to Uncover Downstream Effects of Ascending Aortic Grafts.Annals of biomedical engineering · 2026Article
- Outcomes of Heart Transplantation in Single-Ventricle Physiology: A Retrospective Single-Center Experience with Emphasis on Surgical Complexity.Journal of clinical medicine · 2026Article
- Fabrication and characterization of small-caliber nanofibrous vascular scaffolds with sustained release of endothelial cell derivatives and heparin.Frontiers in bioengineering and biotechnology · 2026Article
- Programmable Compliance in Small-Diameter Vascular Grafts by Design of Melt-Electrowritten Scaffold Architectures for In Situ Tissue Engineering.Advanced healthcare materials · 2026Article
- Effect of stent-graft compliance on hemodynamics and aortic stiffening in an in vivo porcine study.Acta biomaterialia · 2026Article
- Aortic Function in a Longitudinal 4D Flow MRI Study in Marfan Syndrome Patients Receiving Resveratrol.Journal of magnetic resonance imaging : JMRI · 2025Article
- Ascending Aortic Aneurysms: From Pathophysiology to Surgical Repair.Journal of clinical medicine · 2025Review
- Are early outcomes of reoperative aortic root surgery impacted by previous root procedure and indication for reintervention?JTCVS open · 2025Article
- Preoperative vascular dysfunction is associated with acute kidney injury after cardiac surgery.Journal of thoracic disease · 2024Article
- External Scaffold for Strengthening the Pulmonary Autograft in the Ross Procedure.Biomimetics (Basel, Switzerland) · 2024Review
- Bicuspid Aortic Valve in Children and Young Adults for Cardiologists and Cardiac Surgeons: State-of-the-Art of Literature Review.Journal of cardiovascular development and disease · 2024Review
- Comparison of Biomechanical and Microstructural Properties of Aortic Graft Materials in Aortic Repair Surgeries.Journal of functional biomaterials · 2024Article
- Patient-Specific Haemodynamic Analysis of Virtual Grafting Strategies in Type-B Aortic Dissection: Impact of Compliance Mismatch.Cardiovascular engineering and technology · 2024Article
- Research Progress on Aortic Root Aneurysms.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Endovascular Repair of Zone 0 Ascending Aortic Aneurysm: A Review of Current Knowledge and Developing Technology.Aorta (Stamford, Conn.) · 2024Article
- Distal aortic biomechanics after transcatheter versus surgical aortic valve replacement: a hypothesis generating study.Journal of cardiothoracic surgery · 2023Article
- Three-Dimensional Characterization of Aortic Root Motion by Vascular Deformation Mapping.Journal of clinical medicine · 2023Article
- Aortopathies: From Etiology to the Role of Arterial Stiffness.Journal of clinical medicine · 2023Review
- Genetics and mechanisms of thoracic aortic disease.Nature reviews. Cardiology · 2023Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic grafts are widely used in cardiac and vascular surgery since the mid-1970s. Despite their general good performance, inability of mimicking the elastomechanical characteristics of the native arterial tissue, and the consequent lack of adequate compliance, leads to a cascade of hemodynamic and biological alterations deeply affecting cardiovascular homeostasis. Those concerns have been reconsidered in more contemporaneous surgical and experimental reports which also triggered some research efforts in the tissue engineering field towards the realization of biomimetic arterial surrogates. The present review focuses on the significance of the "compliance mismatch" phenomenon occurring after aortic root or ascending aorta replacement with prosthetic grafts and discusses the clinical reflexes of this state of tissue incompatibility, as the loss of the native elastomechanical properties of the aorta can translate into detrimental effects on the normal efficiency of the aortic root complex with impact in the long-term results of patients undergoing aortic replacement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.