ArticleAnnals of clinical microbiology and antimicrobials2016
Identification and antifungal susceptibility of Candida species isolated from bloodstream infections in Konya, Turkey.
Article in Annals of clinical microbiology and antimicrobials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Candida albicans-A systematic review to inform the World Health Organization Fungal Priority Pathogens List.Medical mycology · 2024Pooled it
- Twenty-Year Course of Antifungal Resistance inJournal of fungi (Basel, Switzerland) · 2025Review
- Antifungal Susceptibility Data and Epidemiological Distribution ofAntibiotics (Basel, Switzerland) · 2024Article
- Antifungal Drug Susceptibility Profile ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024Article
- Overview on the Infections Related to RarePathogens (Basel, Switzerland) · 2022Review
- Invasive Candida kefyr infection presenting as pyelonephritis in an ICU hospitalized COVID-19 patient: Case report and review of the literature.Journal de mycologie medicale · 2022Review
- Correlation Between Drug Resistance and Virulence ofInfection and drug resistance · 2022Article
- Biofilm-forming microorganisms causing hospital-acquired infections from intravenous catheter: A systematic review.Current research in microbial sciences · 2022Article
- Promising Anti-Biofilm Agents and Phagocytes Enhancers for the Treatment ofFrontiers in cellular and infection microbiology · 2022Article
- The newly synthesized thiazole derivatives as potential antifungal compounds against Candida albicans.Applied microbiology and biotechnology · 2021Article
- Current and promising pharmacotherapeutic options for candidiasis.Expert opinion on pharmacotherapy · 2021Article
- Drug Resistance and Novel Therapeutic Approaches in Invasive Candidiasis.Frontiers in cellular and infection microbiology · 2021Review
- Candida kefyr in Kuwait: Prevalence, antifungal drug susceptibility and genotypic heterogeneity.PloS one · 2020Article
- Surfactin Like Broad Spectrum Antimicrobial Lipopeptide Co-produced With Sublancin FromFrontiers in microbiology · 2020Article
- Identification ofPathogens (Basel, Switzerland) · 2019Article
- Genetic diversity and antifungal susceptibility of Candida albicans isolated from Iranian patients.Medical mycology · 2019Article
- Antifungal susceptibility pattern and biofilm-related genes expression in planktonic and biofilm cells ofCurrent medical mycology · 2019Article
- Incidence and spectrum of yeast species isolated from the oral cavity of Iranian patients suffering from hematological malignancies.Journal of oral microbiology · 2019Article
- Correlation between antifungal consumption and the distribution of Candida species in different hospital departments of a Lebanese medical Centre.BMC infectious diseases · 2018Article
- Proof of Concept for MBT ASTRA, a Rapid Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS)-Based Method To Detect Caspofungin Resistance in Candida albicans and Candida glabrata.Journal of clinical microbiology · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn this study, our aim was to identify Candida species isolated from bloodstream infections and to determine their susceptibilities to various antifungal agents to demonstrate the local resistance profiles and to guide empirical treatment for clinicians.
methodsTwo hundred Candida isolates (95 Candida albicans, 105 non-albicans Candida strains) were included in the study. Candida species were identified by conventional, biochemical and molecular methods. Antifungal susceptibility tests for amphotericin B, fluconazole, voriconazole, posaconazole, caspofungin and anidulafungin were performed with broth microdilution method according to the Clinical and Laboratory Standards Institute M27-A3 document.
resultsOf the 200 Candida strains, the most prevalent species were C. albicans (47.5 %), Candida glabrata (18.0 %) and Candida parapsilosis complex (14.0 %). All Candida species except for three (1.5 %) Candida kefyr strains were susceptible to amphotericin B. Only one (2.8 %) C. glabrata was resistant to fluconazole (MIC ≥ 64 μg/ml), and the others (97.2 %) exhibited dose-dependent susceptibility. All species, but C. glabrata strains, were susceptible to fluconazole. Resistance to voriconazole, posaconazole, caspofungin and anidulafungin was not detected in any strain.
conclusionCandida albicans were susceptible to all antifungal drugs. Three C. kefyr strains were resistant to amphotericin B. Only one C. glabrata was resistant to fluconazole. All the strains were susceptible to voriconazole, posaconazole, caspofungin and anidulafungin. In vitro antifungal susceptibility tests should be performed to select of appropriate and effective antifungal therapy, and monitor the development of resistance.
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