ArticleClinical rheumatology2016
Psychological factors mediate key symptoms of fibromyalgia through their influence on stress.
Article in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 47 citations in OpenAlex.
- Serum proteome profiles revealed dysregulated proteins and mechanisms associated with fibromyalgia syndrome in women.Scientific reports · 2020Trial
- The role of personality in patients with fibromyalgia.Clinical rheumatology · 2019Trial
- BDNF and IL-33 Dynamics in an Ultrasound Stress Model of Fibromyalgia-like Phenotypes.International journal of molecular sciences · 2026Article
- The Relationship Between Pain and Depression in Fibromyalgia: Structural Equation Modeling and Network Analysis.International journal of environmental research and public health · 2026Article
- Differences in Pressure Pain Threshold and Strain Elastography Between Women with and Without Fibromyalgia: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Physical and Mental Health of Fibromyalgia Patients Following October 7th Attack and the Ensuing Military Conflict: A Cross-Sectional Analysis.European journal of pain (London, England) · 2025Article
- Exercise Intervention in Women with Fibromyalgia and Its Influence on Pain, Psychological Variables, and Disability: An Observational Study.Life (Basel, Switzerland) · 2024Article
- Perceived and endocrine acute and chronic stress indicators in fibromyalgia syndrome.Scientific reports · 2024Article
- Perceived Stress and Life Stressors in Adults with and without Fibromyalgia.Biomedicines · 2024Article
- Nurses' Perceptions of Patient Fibromyalgia Illness Experiences after Performing Group-Based Problem-Solving Therapy: A Qualitative Research Study.Healthcare (Basel, Switzerland) · 2023Article
- Emotional arousal and valence in patients with fibromyalgia: a pilot study.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Do Psychological Factors Influence the Elastic Properties of Soft Tissue in Subjects with Fibromyalgia? A Cross-Sectional Observational Study.Biomedicines · 2022Article
- The Relationship between Daily Physical Activity, Psychological Factors, and Vegetative Symptoms in Women with Fibromyalgia: A Cross-Sectional Observational Study.International journal of environmental research and public health · 2022Observational
- Telemedicine in the Management of Patients with Rheumatic Disease during COVID-19 Pandemic: Incidence of Psychiatric Disorders and Fibromyalgia in Patients with Rheumatoid Arthritis and Psoriatic Arthritis.International journal of environmental research and public health · 2022Article
- Evaluation of Big Five personality factors in women with fibromyalgia: a cross-sectional study.Rheumatology international · 2022Article
- Online Mindfulness Intervention for Inflammatory Bowel Disease: Adherence and Efficacy.Frontiers in psychology · 2021Article
- Article
- Impact of coping strategies on quality of life of adolescents and young women with endometriosis.Journal of psychosomatic obstetrics and gynaecology · 2019Article
- Mindfulness is associated with psychological health and moderates the impact of fibromyalgia.Clinical rheumatology · 2019Article
- Differences in daily objective physical activity and sedentary time between women with self-reported fibromyalgia and controls: results from the Canadian health measures survey.Clinical rheumatology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical features of fibromyalgia are associated with various psychological factors, including stress. We examined the hypothesis that the path that psychological factors follow in influencing fibromyalgia symptoms is through their direct effect on stress. Ninety-eight females with ACR 1990 classified fibromyalgia completed the following questionnaires: The Big 5 Personality Inventory, Fibromyalgia Impact Questionnaire, Perceived Stress Scale, Profile of Mood States, Mastery Scale, and Perceived Control of Internal States Scale. SPSS (PASW version 22) was used to perform basic t tests, means, and standard deviations to show difference between symptom characteristics. Pathway analysis using structural equation modelling (Laavan) examined the effect of stress on the relationships between psychological factors and the elements that define the fibromyalgia phenotype. The preferred model showed that the identified path clearly linked the psychological variables of anxiety, neuroticism and mastery, but not internal control, to the three key elements of fibromyalgia, namely pain, fatigue and sleep (p < 0.001), via the person's perceived stress. Confusion, however, did not fit the preferred model. This study confirms that stress is a necessary link in the pathway between certain identified, established and significant psychological factors and key fibromyalgia symptoms. This has implications for the understanding of contributing mechanisms and the clinical care of patients with fibromyalgia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.