ArticleParasitology research2016
Molecular detection and phylogenetic analysis of Hepatozoon spp. in questing Ixodes ricinus ticks and rodents from Slovakia and Czech Republic.
Article in Parasitology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Hepatozoon (Eucoccidiorida: Hepatozoidae) in wild mammals of the Americas: a systematic review.Parasites & vectors · 2024Pooled it
- Blood parasites and bacteria of Muroidea rodents of the Chornobyl Exclusion Zone.International journal for parasitology. Parasites and wildlife · 2026Article
- Phylogenetic and histopathological characterization of putative Hepatozoon ophisauri-like lineages in rodents from Italy.Acta parasitologica · 2026Article
- First Molecular Evidence and Phylogeny ofVeterinary sciences · 2025Article
- First report of Hepatozoon and Lankesterella spp. infections in wild rodents from Pakistan, and their potential impact on blood parameters and oxidative stress markers in vital organs.Veterinary research communications · 2024Article
- Pathogens detected in ticks (Ixodes ricinus) feeding on red squirrels (Sciurus vulgaris) from city parks in Warsaw.Experimental & applied acarology · 2024Article
- Phylogenetic analysis of a novel Hepatozoon species (Hepatozoon sp. SK3) and an additional yet unknown Hepatozoon species (Hepatozoon sp. BV2) besides H. erhardovae in small rodents from Central Europe.Parasitology research · 2024Article
- The role of wildlife in the epidemiology of tick-borne diseases in Slovakia.Current research in parasitology & vector-borne diseases · 2024Review
- The first report on Hepatozoon canis in dogs and wolves in Poland: clinical and epidemiological features.Parasites & vectors · 2023Article
- Diversity of Hepatozoon species in wild mammals and ticks in Europe.Parasites & vectors · 2023Article
- First report on detection ofFrontiers in veterinary science · 2023Article
- First autochthonous clinical case of Hepatozoon silvestris in a domestic cat in Italy with unusual presentation.Parasites & vectors · 2022Article
- Article
- First Record ofMicroorganisms · 2022Article
- Review
- What do we know about the microbiome ofFrontiers in cellular and infection microbiology · 2022Review
- Upscaling the Surveillance of Tick-borne Pathogens in the French Caribbean Islands.Pathogens (Basel, Switzerland) · 2020Article
- Blood parasites (Babesia, Hepatozoon and Trypanosoma) of rodents, Lithuania: part I. Molecular and traditional microscopy approach.Parasitology research · 2020Article
- Genetic diversity of Hepatozoon spp. in rodents from Brazil.Scientific reports · 2019Article
- Long-term trends of tick-borne pathogens in regard to small mammal and tick populations from Saxony, Germany.Parasites & vectors · 2019Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By amplification and sequencing of 18S rRNA gene fragments, Hepatozoon spp. DNA was detected in 0.08 % (4/5057) and 0.04 % (1/2473) of questing Ixodes ricinus ticks from Slovakia and Czech Republic, respectively. Hepatozoon spp. DNA was also detected in spleen and/or lungs of 4.45 % (27/606) of rodents from Slovakia. Prevalence of infection was significantly higher in Myodes glareolus (11.45 %) than in Apodemus spp. (0.28 %) (P < 0.001). Sequencing of 18S rRNA Hepatozoon spp. gene amplicons from I. ricinus showed 100 % identity with Hepatozoon canis isolates from red foxes or dogs in Europe. Phylogenetic analysis showed that at least two H. canis 18S rRNA genotypes exist in Slovakia of which one was identified also in the Czech Republic. The finding of H. canis in questing I. ricinus suggests the geographical spread of the parasite and a potential role of other ticks as its vectors in areas where Rhipicephalus sanguineus is not endemic. Sequencing of 18S rRNA gene amplicons from M. glareolus revealed the presence of two closely related genetic variants, Hepatozoon sp. SK1 and Hepatozoon sp. SK2, showing 99-100 % identity with isolates from M. glareolus from other European countries. Phylogenetic analysis demonstrates that 18S rRNA variants SK1 and SK2 correspond to previously described genotypes UR1 and UR2 of H. erhardovae, respectively. The isolate from Apodemus flavicollis (Hepatozoon sp. SK3b) was 99 % identical with isolates from reptiles in Africa and Asia. Further studies are necessary to identify the taxonomic status of Hepatozoon spp. parasitizing rodents in Europe and the host-parasite interactions in natural foci.
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