Evidence map›Paper›PMID 27242708›Full record

ArticleFrontiers in microbiology2016

Antimicrobial Activity of Tulsi (Ocimum tenuiflorum) Essential Oil and Their Major Constituents against Three Species of Bacteria.

Hanaa A Yamani, Edwin C Pang, Nitin Mantri, Margaret A Deighton

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 185 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Plants (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Bioactive compound identification without fractionation: an Ocimum spp. case study.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  10. Article
  11. Antibacterial Activity ofJournal of microbiology and biotechnology · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Is Camphor the Future in Supporting Therapy for Skin Infections?Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Hanaa A YamaniSchool of Science, Royal Melbourne Institute of Technology UniversityMelbourne, VIC, Australia; Biology, Section Microbiology, School of Applied Sciences, King Abdulaziz UniversityJeddah, Saudi Arabia.
Edwin C PangSchool of Science, Royal Melbourne Institute of Technology University Melbourne, VIC, Australia.
Nitin MantriSchool of Science, Royal Melbourne Institute of Technology University Melbourne, VIC, Australia.
Margaret A DeightonSchool of Science, Royal Melbourne Institute of Technology University Melbourne, VIC, Australia.
RMIT University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years scientists worldwide have realized that the effective life span of any antimicrobial agent is limited, due to increasing development of resistance by microorganisms. Consequently, numerous studies have been conducted to find new alternative sources of antimicrobial agents, especially from plants. The aims of this project were to examine the antimicrobial properties of essential oils distilled from Australian-grown Ocimum tenuiflorum (Tulsi), to quantify the volatile components present in flower spikes, leaves and the essential oil, and to investigate the compounds responsible for any activity. Broth micro-dilution was used to determine the minimum inhibitory concentration (MIC) of Tulsi essential oil against selected microbial pathogens. The oils, at concentrations of 4.5 and 2.25% completely inhibited the growth of Staphylococcus aureus (including MRSA) and Escherichia coli, while the same concentrations only partly inhibited the growth of Pseudomonas aeruginosa. Of 54 compounds identified in Tulsi leaves, flower spikes, or essential oil, three are proposed to be responsible for this activity; camphor, eucalyptol and eugenol. Since S. aureus (including MRSA), P. aeruginosa and E. coli are major pathogens causing skin and soft tissue infections, Tulsi essential oil could be a valuable topical antimicrobial agent for management of skin infections caused by these organisms.

Indexed as

antimicrobial activityessential oilgas chromatography–mass spectrometryheadspace–solid phase microextractionTulsi (Ocimum tenuiflorum)

Identifiers

PMID27242708
PMCPMC4868837
OpenAlexW2395265425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.