ReviewFrontiers in endocrinology2016
Which Is the Ideal Treatment for Benign Diffuse and Multinodular Non-Toxic Goiters?
Review in Frontiers in endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Management of a huge cystic multi-nodular goiter with retro-sternal extension. Case report.International journal of surgery case reports · 2025Article
- Transcervical and robotic-assisted thoracoscopic resection of a substernal goiter.BMJ case reports · 2022Article
- Impact of thyroidectomy on quality of life in benign goitres: results from a prospective cohort study.Langenbeck's archives of surgery · 2022Article
- Thyroid dysfunction in Greece: Results from the national health examination survey EMENO.PloS one · 2022Article
- Radiofrequency Ablation a Safe and Effective Treatment for Pediatric Benign Nodular Thyroid Goiter.Frontiers in pediatrics · 2021Article
- [The thyroid gland in old age : Physiology and pathology].Wiener medizinische Wochenschrift (1946) · 2020Article
- A Review of the Pathology, Diagnosis and Management of Colloid Goitre.European endocrinology · 2020Review
- The Efficacy of Ultrasonography-Guided Radiofrequency Ablation in Patients With Benign Thyroid Goiters With a History of Unilateral Lobectomy.Clinical and experimental otorhinolaryngology · 2020Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with large benign goiters often present local compressive symptoms that require surgical treatment, including dysphagia, neck tightness, and airway obstruction. In contrast, patients with such goiters who remain asymptomatic may be observed after exclusion of malignancy. The use of levothyroxine (LT4) to reduce the volume of the goiter is still a controversial treatment for large goiters, and the optimal surgical procedure for multinodular goiter is still debatable. Radioiodine is a safe and effective treatment option when used alone or in combination with recombinant human TSH. This review discusses current therapeutic options to treat diffuse and multinodular non-toxic benign goiters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.