ReviewFrontiers in endocrinology2016
Comparative Effect of ACTH and Related Peptides on Proliferation and Growth of Rat Adrenal Gland.
Review in Frontiers in endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Stress-associated transient enlargement of pre-existing adrenal hyperplasia in 21-hydroxylase deficiency: a case report.Frontiers in endocrinology · 2026Article
- Article
- Elevated luteinizing hormone receptor signaling or selenium treatment leads to comparable changes in adrenal cortex histology and androgen-AR/ZIP9 signaling.Protoplasma · 2024Article
- Effects of vitamin C and early-age thermal conditioning on pituitary adrenocorticotropic hormone cells in broilers chronically exposed to heat stress: an immunohistomorphometric and hormonal study.Veterinary research forum : an international quarterly journal · 2024Article
- Major depressive disorder and bistability in an HPA-CNS toggle switch.PLoS computational biology · 2023Article
- Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues.European journal of endocrinology · 2022Article
- [Adrenal glands stem cells: general signaling pathways].Problemy endokrinologii · 2021Article
- Article
- Hormone seasonality in medical records suggests circannual endocrine circuits.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- A Moderate Increase in Ambient Temperature Influences The Structure and Hormonal Secretion of Adrenal Glands in Rats.Cell journal · 2021Article
- Embryonic Development and Adult Regeneration of the Adrenal Gland.Endocrinology and metabolism (Seoul, Korea) · 2020Review
- A new model for the HPA axis explains dysregulation of stress hormones on the timescale of weeks.Molecular systems biology · 2020Article
- Regulation of stem and progenitor cells in the adrenal cortex.Current opinion in endocrine and metabolic research · 2019Article
- Prss56 expression in the rodent hypothalamus: Inverse correlation with pro-opiomelanocortin suggests oscillatory gene expression in adult rat tanycytes.The Journal of comparative neurology · 2018Article
- POMC: The Physiological Power of Hormone Processing.Physiological reviews · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pro-opiomelanocortin (POMC) is a polypeptide precursor known to yield biologically active peptides related to a range of functions. These active peptides include the adrenocorticotropic hormone (ACTH), which is essential for maintenance of adrenal growth and steroidogenesis, and the alpha-melanocyte stimulation hormone, which plays a key role in energy homeostasis. However, the role of the highly conserved N-terminal region of POMC peptide fragments has begun to be unraveled only recently. Here, we review the cascade of events involved in regulation of proliferation and growth of murine adrenal cortex triggered by ACTH and other POMC-derived peptides. Key findings regarding signaling pathways and modulation of genes and proteins required for the regulation of adrenal growth are summarized. We have outlined the known mechanisms as well as future challenges for research on the regulation of adrenal proliferation and growth triggered by these peptides.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.