ArticleFrontiers in psychiatry2016
Tic Frequency Decreases during Short-term Psychosocial Stress - An Experimental Study on Children with Tic Disorders.
Article in Frontiers in psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 28 citations in OpenAlex.
- Changes in Heart Rate Variability in Adolescent Patients With Tic Disorders: A 1-Year Prospective Study.Psychiatry investigation · 2025Article
- The role of neuroactive steroids in tic disorders.Neuroscience and biobehavioral reviews · 2024Review
- Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Emotion regulation and tic disorders in children.European child & adolescent psychiatry · 2023Article
- Why Tic Severity Changes from Then to Now and from Here to There.Journal of clinical medicine · 2022Review
- Hair cortisol-a stress marker in children and adolescents with chronic tic disorders? A large European cross-sectional study.European child & adolescent psychiatry · 2022Article
- Allopregnanolone: The missing link to explain the effects of stress on tic exacerbation?Journal of neuroendocrinology · 2022Review
- Article
- Networks in the Field of Tourette Syndrome.Frontiers in neurology · 2021Review
- European Multicentre Tics in Children Studies (EMTICS): protocol for two cohort studies to assess risk factors for tic onset and exacerbation in children and adolescents.European child & adolescent psychiatry · 2019Article
- A Review of Behavioral Observation Coding Approaches for the Trier Social Stress Test for Children.Frontiers in psychology · 2018Article
- What makes you tic? Translational approaches to study the role of stress and contextual triggers in Tourette syndrome.Neuroscience and biobehavioral reviews · 2017Review
- Tourette syndrome research highlights from 2016.F1000Research · 2017Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been suggested that psychosocial stress influences situational fluctuations of tic frequency. However, evidence from experimental studies is lacking. The current study investigated the effects of the Trier Social Stress Test (TSST-C) on tic frequency in 31 children and adolescents with tic disorders. A relaxation and a concentration situation served as control conditions. Patients were asked either to suppress their tics or to "tic freely." Physiological measures of stress were measured throughout the experiment. The TSST-C elicited a clear stress response with elevated levels of saliva cortisol, increased heart rate, and a larger number of skin conductance responses. During relaxation and concentration, the instruction to suppress tics reduced the number of tics, whereas during stress, the number of tics was low, regardless of the given instruction. Our study suggests that the stress might result in a situational decrease of tic frequency.
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