Evidence map›Paper›PMID 27242469›Full record

ReviewFrontiers in human neuroscience2016

tDCS of the Cerebellum: Where Do We Stand in 2016? Technical Issues and Critical Review of the Literature.

Kim van Dun, Florian C A A Bodranghien, Peter Mariën, Mario U Manto

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 69 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05781412 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Modulation of the Activity in the Cerebellum With Transcranial Direct Current Stimulation in Autistic Participants

TypeinterventionalSponsorBeatriz CatoiraRan2022 to 2024Enrolled100ConditionsAutism Spectrum DisorderArmstDCS
NCT05963321 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Cortical Excitability Modulation With Cerebellar Transcranial Direct Current Stimulation in Fibromyalgia: a Randomized Clinical Trial

TypeinterventionalSponsorHospital de Clinicas de Porto AlegreRan2023 to 2026Enrolled92ConditionsFibromyalgia, Chronic PainArmsTDCS
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  14. Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia Type 3: a Randomized, Double-Blind, Sham-Controlled Trial.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kim van DunClinical and Experimental Neurolinguistics, Vrije Universiteit Brussel Brussels, Belgium.
Florian C A A BodranghienUnité d'Etude du Mouvement, Laboratoire de Neurologie Expérimentale, Université libre de Bruxelles (ULB) Brussels, Belgium.
Peter MariënClinical and Experimental Neurolinguistics, Vrije Universiteit BrusselBrussels, Belgium; Department of Neurology and Memory Clinic, ZNA Middelheim General HospitalAntwerp, Belgium.
Mario U MantoUnité d'Etude du Mouvement, Laboratoire de Neurologie Expérimentale, Université libre de Bruxelles (ULB)Brussels, Belgium; Service des Neurosciences, Université de MonsMons, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial Direct Current Stimulation (tDCS) is an up-and-coming electrical neurostimulation technique increasingly used both in healthy subjects and in selected groups of patients. Due to the high density of neurons in the cerebellum, its peculiar anatomical organization with the cortex lying superficially below the skull and its diffuse connections with motor and associative areas of the cerebrum, the cerebellum is becoming a major target for neuromodulation of the cerebellocerebral networks. We discuss the recent studies based on cerebellar tDCS with a focus on the numerous technical and open issues which remain to be solved. Our current knowledge of the physiological impacts of tDCS on cerebellar circuitry is criticized. We provide a comparison with transcranial Alternating Current Stimulation (tACS), another promising transcranial electrical neurostimulation technique. Although both tDCS and tACS are becoming established techniques to modulate the cerebellocerebral networks, it is surprising that their impacts on cerebellar disorders remains unclear. A major reason is that the literature lacks large trials with a double-blind, sham-controlled, and cross-over experimental design in cerebellar patients.

Indexed as

anodal vs. cathodalcerebellumelectrode placementintensityoffline vs. onlineshamtACStDCS

Identifiers

PMID27242469
PMCPMC4862979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.