ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2017
Association between vascular access creation and deceleration of estimated glomerular filtration rate decline in late-stage chronic kidney disease patients transitioning to end-stage renal disease.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 55 citations in OpenAlex.
- Multicenter Investigation of the Initial Hemodialysis Vascular Access and Its Related Factors in Hangzhou of China.BioMed research international · 2021Trial
- Nondialytic Care vs Dialysis Transition on Hospitalization: Outcomes in Veterans With Advanced Chronic Kidney Disease.Mayo Clinic proceedings · 2026Article
- Gender Disparities in Secondary Patency of Arteriovenous Fistulas: Insights into Hemodialysis Outcomes and Long-Term Vascular Access Viability.Journal of clinical medicine · 2026Article
- Evaluating the impact of Arteriovenous Fistula (AVF) creation on kidney function.Journal of nephrology · 2025Observational
- Vascular Access Management After Kidney Transplantation Position Paper on Behalf of the Vascular Access Society and the European Kidney Transplant Association.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Impact of arteriovenous fistula formation on trajectory of kidney function decline: a target trial emulation.Clinical kidney journal · 2024Article
- Cardiac implications of upper-arm arteriovenous fistulas: A case series.The journal of vascular access · 2023Article
- Laxative use in patients with advanced chronic kidney disease transitioning to dialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Article
- Flow reduction of a high-flow arteriovenous fistula in a hemodialysis patient reveals changes in natriuretic and renin-angiotensin system hormones of relevance for kidney function.Physiological reports · 2021Article
- Laxative Use and Change in Estimated Glomerular Filtration Rate in Patients With Advanced Chronic Kidney Disease.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2021Article
- Suboptimal dialysis initiation is associated with comorbidities and uraemia progression rate but not with estimated glomerular filtration rate.Clinical kidney journal · 2021Article
- Longer Predialysis ACEi/ARB Utilization Is Associated With Reduced Postdialysis Mortality.The American journal of medicine · 2020Article
- Association between Posttransplant Opioid Use and Immunosuppressant Therapy Adherence among Renal Transplant Recipients.Nephron · 2020Article
- Impact of Arteriovenous fistula creation on estimated glomerular filtration rate decline in Predialysis patients.BMC nephrology · 2019Article
- Response to "The Effect of Arteriovenous Fistula on Hard Endpoints Should be Observed Prospectively in Both CKD and Non-CKD Patients".American journal of hypertension · 2019Article
- Effect of Arteriovenous Fistula Creation on Systolic and Diastolic Blood Pressure in Patients With Pre-dialysis Advanced Chronic Kidney Disease.American journal of hypertension · 2019Article
- History of posttraumatic stress disorder and outcomes after kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Article
- Effect of arteriovenous access closure and timing on kidney function in kidney transplant recipients.PloS one · 2019Article
- Controversies in the management of the haemodialysis-related arteriovenous fistula following kidney transplantation.Clinical kidney journal · 2018Article
- Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.Kidney international · 2018Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPrior studies have suggested that arteriovenous fistula (AVF) or graft (AVG) creation may be associated with slowing of estimated glomerular filtration rate (eGFR) decline. It is unclear if this is attributable to the physiological benefits of a mature access on systemic circulation versus confounding factors.
methodsWe examined a nationwide cohort of 3026 US veterans with advanced chronic kidney disease (CKD) transitioning to dialysis between 2007 and 2011 who had a pre-dialysis AVF/AVG and had at least three outpatient eGFR measurements both before and after AVF/AVG creation. Slopes of eGFR were estimated using mixed-effects models adjusted for fixed and time-dependent confounders, and compared separately for the pre- and post-AVF/AVG period overall and in patients stratified by AVF/AVG maturation. In all, 3514 patients without AVF/AVG who started dialysis with a catheter served as comparators, using an arbitrary 6-month index date before dialysis initiation to assess change in eGFR slopes.
resultsOf the 3026 patients with AVF/AVG (mean age 67 years, 98% male, 75% diabetic), 71% had a mature AVF/AVG at dialysis initiation. eGFR decline accelerated in the last 6 months prior to dialysis in patients with a catheter (median, from -6.0 to -16.3 mL/min/1.73 m2/year, P < 0.001), while a significant deceleration of eGFR decline was seen after vascular access creation in those with AVF/AVG (median, from -5.6 to -4.1 mL/min/1.73 m2/year, P < 0.001). Findings were independent of AVF/AVG maturation status and were robust in adjusted models.
conclusionsThe creation of pre-dialysis AVF/AVG appears to be associated with eGFR slope deceleration and, consequently, may delay the onset of dialysis initiation in advanced CKD patients.
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Registered trials
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