Evidence map›Paper›PMID 27242315›Full record

ArticleJournal of hepatology2016

Resurrection of response-guided therapy for sofosbuvir combination therapies.

Harel Dahari, Phillippe Halfon, Scott J Cotler

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Early HCV viral kinetics under DAAs may optimize duration of therapy in patients with compensated cirrhosis.Liver international : official journal of the International Association for the Study of the Liver · 2019
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Harel DahariThe Program for Experimental and Theoretical Modeling, Division of Hepatology, Loyola University Medical Center, Maywood, IL, USA. Electronic address: hdahari@lumc.edu.
Phillippe HalfonInternal Medecine and Infectious Disease Hopital Europeen, Laboratoire Alphabio, Marseille, France.
Scott J CotlerThe Program for Experimental and Theoretical Modeling, Division of Hepatology, Loyola University Medical Center, Maywood, IL, USA.

Funding

Collaborative Integration of HCV Molecular Virology and Mathematical ModelingR01AI078881 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PERELSON, ALAN S, UPRICHARD, SUSAN L. · 2011 to 2025
$7.5M
NIAID NIH HHS R01 AI078881
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hepatitis C, ChronicSofosbuvirAntiviral AgentsDrug Therapy, CombinationGenotypeHepacivirusHumansRibavirinAntiviral AgentsRibavirinSofosbuvir

Identifiers

PMID27242315
PMCPMC5072361

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.