Evidence map›Paper›PMID 27242194›Full record

ArticleTrends in biochemical sciences2016

Blind Evaluation of Hybrid Protein Structure Analysis Methods based on Cross-Linking.

Adam Belsom, Michael Schneider, Oliver Brock, Juri Rappsilber

Abstract read
In one paragraph

Article in Trends in biochemical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Protein Secondary Structure Patterns in Short-Range Cross-Link Atlas.Angewandte Chemie (International ed. in English) · 2025
    Article
  2. Article
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  5. Mapping low-affinity/high-specificity peptide-protein interactions using ligand-footprinting mass spectrometry.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adam BelsomWellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK.
Michael SchneiderRobotics and Biology Laboratory, Department of Electrical Engineering and Computer Science, Technische Universität Berlin, 10587 Berlin, Germany.
Oliver BrockRobotics and Biology Laboratory, Department of Electrical Engineering and Computer Science, Technische Universität Berlin, 10587 Berlin, Germany.
Juri RappsilberWellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK; Chair of Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany. Electronic address: juri.rappsilber@ed.ac.uk.

Funding

Wellcome Trust 092076Wellcome Trust 103139Wellcome Trust 103139/Z/13/ZWellcome Trust 108504
6 · The paper itself

Abstract

Hybrid methods combine experimental data and computational modeling to analyze protein structures that are elusive to structure determination. To spur the development of hybrid methods, we propose to test them in the context of the CASP experiment and would like to invite experimental groups to participate in this initiative.

Indexed as

Models, MolecularCross-Linking ReagentsMass SpectrometryProtein ConformationProteinsCross-Linking ReagentsProteins

Identifiers

PMID27242194
PMCPMC4929974

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.