Evidence map›Paper›PMID 27241737›Full record

ArticleBiomedical and environmental sciences : BES2016

Effects of Parental Dietary Exposure to GM Rice TT51 on the Male Reproductive System of Rat Offspring.

Er Hui Wang, Zhou Yu, Xu Dong Jia, Wen Zhong Zhang, Hai Bin Xu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical and environmental sciences : BES, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Er Hui WangDepartment of Nutrition and Food Hygiene, College of Public Health, Xinxiang Medical University, Xinxiang 453003, Henan, China; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, Henan, China; China National Center for Food Safety Risk Assessment, Beijing 100021, China.
Zhou YuChina National Center for Food Safety Risk Assessment, Beijing 100021, China.
Xu Dong JiaChina National Center for Food Safety Risk Assessment, Beijing 100021, China.
Wen Zhong ZhangChina National Center for Food Safety Risk Assessment, Beijing 100021, China.
Hai Bin XuChina National Center for Food Safety Risk Assessment, Beijing 100021, China.
China National Center for Food Safety Risk Assessment · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the health effects of parental dietary exposure to GM rice TT51 on the male reproductive system of rat off spring.

methodsRice-based diets, containing 60% ordinary grocery rice, MingHui63, or TT51 by weight, were given to parental rats (15 males/30 females each group) for 70 days prior mating and throughout pregnancy and lactation. After weaning, eight male offspring rats were randomly selected at each group and fed with diets correspondent to their parents' for 70 days. The effects of exposure to TT51 on male reproductive system of offspring rats were assessed through sperm parameters, testicular function enzyme activities, serum hormones (FSH, LH, and testosterone levels), testis histopathological examination, and the relative expression levels of selected genes along the hypothalamic-pituitary- testicular (HPT) axis.

resultsNo significant differences were observed in body weight, food intake, organ/body weights, serum hormone, sperm parameters, testis function enzyme ACP, LDH, and SDH activities, testis histopathological changes, and relative mRNA expression levels of GnRH-R, FSH-R, LH-R, and AR along the HPT axis.

conclusionThe results of this study demonstrate that parental dietary exposure to TT51 reveals no significant differences on the reproductive system of male offspring rats compared with MingHui63 and control.

Indexed as

DietAnimalsFemaleGenitalia, MaleMaleOryzaPlants, Genetically ModifiedRandom AllocationRatsRats, WistarGenetically modified riceHypothalamic-pituitary-testicular axisReproductive toxicitySperm parameter

Identifiers

PMID27241737
PMCPMC7135354
OpenAlexW2402985406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.