ArticleThe Indian journal of medical research2016
Emergence of vanA gene among vancomycin-resistant enterococci in a tertiary care hospital of North - East India.
Article in The Indian journal of medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Global Prevalence of Vancomycin-Resistant Enterococcus faecium and Enterococcus faecalis Isolated From Clinical and Environmental Sources: A Systematic Review and Meta-Analysis.MicrobiologyOpen · 2026Pooled it
- Prevalence of vancomycin-resistant Enterococci in India between 2000 and 2022: a systematic review and meta-analysis.Antimicrobial resistance and infection control · 2023Pooled it
- Detection of Vancomycin Resistance Enterococcus Species Holding Genes vanA, vanB, vanC1, vanC2, and vanC3 Isolated from Urinary Tract Infections.Biochemical genetics · 2026Article
- Vancomycin-Resistant Enterococcus in Wild Animals: A Global Scoping Review.MicrobiologyOpen · 2026Article
- An Overview ofIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Molecular Epidemiology ofAntibiotics (Basel, Switzerland) · 2025Article
- Presence of multiple van genes among glycopeptide non-susceptible Staphylococcus aureus exhibiting in vitro MIC creep phenomenon: A study from north-east India.The Indian journal of medical research · 2024Article
- Targeted elimination of Vancomycin resistance gene vanA by CRISPR-Cas9 system.BMC microbiology · 2023Article
- Vancomycin and Linezolid-Resistant Enterococcus Isolates from a Tertiary Care Center in India.Diagnostics (Basel, Switzerland) · 2023Article
- Agarose Gel Electrophoresis-Based RAPD-PCR-An Optimization of the Conditions to Rapidly Detect Similarity of the Alert Pathogens for the Purpose of Epidemiological Studies.Gels (Basel, Switzerland) · 2022Article
- Antibiogram Pattern and Virulence Trait Characterization ofJournal of laboratory physicians · 2022Article
- Genotypic characterization of vancomycin-resistantThe Indian journal of medical research · 2022Article
- Single-dose and Steady-state Pharmacokinetics of Vancomycin in Critically Ill Patients Admitted to Medical Intensive Care Unit of India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Linezolid and Vancomycin Resistant Enterococci: A Therapeutic Problem.Journal of clinical and diagnostic research : JCDR · 2017Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesVancomycin-resistant enterococci (VRE) have become one of the most challenging nosocomial pathogens with the rapid spread of the multi-drug resistant strain with limited therapeutic options. It is a matter of concern due to its ability to transfer vancomycin resistant gene to other organisms. The present study was undertaken to determine the emergence of vancomycin-resistant enterococci and the vanA gene among the isolates in a tertiary care hospital of North-East India.
methodsA total of 67 consecutive enterococcal isolates from different clinical samples were collected and identified by using the standard methods. Antibiogram was done by disk diffusion method and VRE was screened by the disk diffusion and vancomycin supplement agar dilution method. The minimum inhibitory concentration (MIC) value for vancomycin was determined by E-test. The VRE isolates were analyzed by PCR for vanA gene.
resultsA total of 54 (81%) Enterococcus faecalis and 13 (19%) E. faecium were detected among the clinical isolates and 16 (24%) were VRE. The VRE isolates were multidrug resistant and linezolid resistance was also found to be in three. MIC range to vancomycin was 16-32 µg/ml among the VRE. The vanA gene was found in nine of 16 VRE isolates. INTERPRETATION &
conclusionsEmergence of VRE and presence of vanA in a tertiary care hospital setting in North-East India indicate toward a need for implementing infection control policies and active surveillance.
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