ArticleThe Journal of infection2016
Respiratory syncytial virus infection in infants in rural Nepal.
Article in The Journal of infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Systematic literature review of the signs and symptoms of respiratory syncytial virus.Influenza and other respiratory viruses · 2023Pooled it
- Respiratory infections in children born preterm in low and middle-income countries: A systematic review.Pediatric pulmonology · 2022Pooled it
- Incidence of respiratory syncytial virus infections among children in rural Bangladesh: a prospective observational study (2021-2023).The Lancet regional health. Southeast Asia · 2026Article
- Identification of key clinical features for pediatric respiratory syncytial virus infection using machine learning.BMC pediatrics · 2026Article
- Cost-effectiveness of introducing a maternal vaccine or long-acting monoclonal antibody to prevent infant respiratory syncytial virus disease in Nepal.Journal of global health · 2025Article
- Respiratory syncytial virus hospitalization costs, rates, and seasonality in Asia: a systematic review and meta-analysis.EClinicalMedicine · 2025Review
- Assessing the cost of illness of RSV and non-RSV acute respiratory infections in Nepali children.Journal of global health · 2025Observational
- Modified Tal Score as a Predictor of Outcome in Bronchiolitis: A Cross-Sectional Study in Nepal.Cureus · 2024Article
- Respiratory syncytial virus burden in children under 2 years old in understudied areas worldwide: gap analysis of available evidence, 2012-2022.Frontiers in pediatrics · 2024Review
- The Impact of Maternal Human Immunodeficiency Virus Infection on the Burden of Respiratory Syncytial Virus Among Pregnant Women and Their Infants, Western Kenya.The Journal of infectious diseases · 2022Article
- Respiratory syncytial virus in severe lower respiratory infections in previously healthy young Ethiopian infants.BMC pediatrics · 2021Article
- Respiratory viral coinfection in a birth cohort of infants in rural Nepal.Influenza and other respiratory viruses · 2020Article
- Primary and Repeated Respiratory Viral Infections Among Infants in Rural Nepal.Journal of the Pediatric Infectious Diseases Society · 2020Article
- Predictors of Poor Outcomes Among Infants With Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana.The Pediatric infectious disease journal · 2019Article
- Breast Milk Prefusion F Immunoglobulin G as a Correlate of Protection Against Respiratory Syncytial Virus Acute Respiratory Illness.The Journal of infectious diseases · 2019Article
- Burden and Risk Factors for Coronavirus Infections in Infants in Rural Nepal.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study.Lancet (London, England) · 2018Observational
- Transplacental transfer of maternal respiratory syncytial virus (RSV) antibody and protection against RSV disease in infants in rural Nepal.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
Abstract
objectivesRespiratory syncytial virus (RSV) pneumonia is a leading cause of infant mortality worldwide. The risk of RSV infection associated with preterm birth is not well-characterized in resource-limited settings. We aimed to obtain precise estimates of risk factors and disease burden of RSV in infants in rural southern Nepal.
methodsPregnant women were enrolled, and along with their infants, followed to six months after birth with active weekly home-based surveillance for acute respiratory illness (ARI). Mid-nasal swabs were obtained and tested for RSV by PCR for all illness episodes. Birth outcomes were assessed at a postpartum home visit.
results311 (9%) of 3509 infants had an RSV ARI. RSV ARI incidence decreased from 551/1000 person-years in infants born between 28 and 31 weeks to 195/1000 person-years in infants born full-term (p = 0.017). Of 220 infants (71%) evaluated in the health system, 41 (19%) visited a hospital or physician. Of 287 infants with an assessment performed, 203 (71%) had a lower respiratory tract infection.
conclusionsIn a rural south Asian setting with intensive home-based surveillance, RSV caused a significant burden of respiratory illness. Preterm infants had the highest incidence of RSV ARI, and should be considered a priority group for RSV preventive interventions in resource-limited settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.