ArticleSpinal cord2017
Demographics of tuberculosis of spine and factors affecting neurological improvement in patients suffering from tuberculosis of spine: a retrospective analysis of 312 cases.
Article in Spinal cord, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Treatment for tuberculosis of the subaxial cervical spine: a systematic review.Archives of orthopaedic and trauma surgery · 2021Pooled it
- Analysis of Treatment and Prognosis of 863 Patients with Spinal Tuberculosis in Guizhou Province.BioMed research international · 2018Trial
- Uncommon Sacroiliac and Presacral Tuberculosis Mimicking Chronic Low Back Pain in a Young Female.Annals of African medicine · 2026Article
- Development and internal validation of a frailty risk stratification model for older patients with spinal tuberculosis.Frontiers in medicine · 2026Article
- Tuberculous Spondylodiscitis in South East Tunisia: Features and Predictive Factors of Poor Prognosis.Cureus · 2025Article
- Spinal tuberculosis treatment duration: Correlating MRI findings with therapeutic outcomes.GMS hygiene and infection control · 2025Article
- Clinical effect of posterior-only approach debridement, intervertebral fusion, and internal fixation for upper thoracic tuberculosis.Acta orthopaedica et traumatologica turcica · 2024Article
- A Comparative Study of Anterior and Posterior Tuberculosis Lesions for the Treatment of Thoracolumbar Tuberculosis disease: A Single Institution Experience in a Major Academic Hospital.Infection and drug resistance · 2024Article
- Spinal Tuberculosis: Features and Early Predictive Factors of Poor Outcomes.Mediterranean journal of rheumatology · 2023Article
- Tuberculosis of the spine.World journal of orthopedics · 2023Review
- Comparative efficacy of traditional conservative treatment and CT-guided local chemotherapy for mild spinal tuberculosis.BMC musculoskeletal disorders · 2022Article
- Severe Kyphotic Deformity Involving Thoracolumbar Region -A Management Dilemma.Journal of orthopaedic case reports · 2021Article
- Midterm surgical results of the lamina with spinous process in treating one-level thoracic or lumbar tuberculosis: a retrospective study.Scientific reports · 2020Article
- CT-guided discitis-osteomyelitis biopsies with negative microbiology: how many days should we wait before repeating the biopsy?Skeletal radiology · 2020Article
- Anterior debridement and fusion using expandable mesh cage only for the treatment of paraparese due to spondylitis tuberculosis: A case report.International journal of surgery case reports · 2020Article
- Characteristics and Management of Spinal Tuberculosis in Tuberculosis Endemic Area of Guizhou Province: A Retrospective Study of 597 Patients in a Teaching Hospital.BioMed research international · 2020Article
- Clinical efficacy of three types of autogenous bone grafts in treatment of single-segment thoracic tuberculosis: A retrospective cohort study.International journal of medical sciences · 2020Article
- Minimally invasive technique for the abscess drainage in lumbosacral tuberculosis using arthroscopy sheath: A case report.International journal of surgery case reports · 2020Article
- Article
- Evaluation and Management of Pyogenic and Tubercular Spine Infections.Current reviews in musculoskeletal medicine · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of the study was to study demographics of tuberculosis of spine and analyze factors that might affect neurological improvement in such patients.
methodsOf the 638 suspected cases of spinal tuberculosis, 312 cases with confirmed diagnosis with at least 1-year follow-up were selected for retrospective analysis. Two hundred cases who presented with neurological deficit were further divided into three groups-completely improved, partially improved and no improvement according to American Spinal Injury Association impairment scale (AIS) grading. All continuous variables and categorical variables were compared across groups.
resultsA total of 209 (66.99%) patients had typical clinical presentation. A total of 264 (84.62%) had typical magnetic resonance imaging (MRI) presentation. Among 356 involved vertebrae, thoracic levels (T1-10) were most commonly affected in 163 (45.78%) followed by thoracolumbar (T11-L2) vertebrae in 98 (27.52%). In 250 patients (80.12%), disease was restricted to one or two adjoining vertebrae. At presentation, 112 (35.89%) patients were neurologically intact, whereas 97 (31%) were AIS D, 65 (20.83%) were AIS C, 8 (2.5%) were AIS B and 30 (9.61%) were AIS A. On statistical analysis, although three groups of patients with complete improvement, partial improvement and no improvement were similar in age, sex, radiological presentation, and co-morbidities and the presence of pulmonary tuberculosis, they were significantly different with regard to the levels of vertebral involvement, AIS grade at presentation, bladder and bowel involvement and its duration.
conclusionsIn management of patients suffering from tuberculosis of spine, levels of vertebral involvement, AIS grade at presentation, bladder and bowel involvement and its duration significantly affect the final neurological improvement.
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