Evidence map›Paper›PMID 27241354›Full record

ReviewHeart rhythm2016

Ablating atrial fibrillation: A translational science perspective for clinicians.

James N Weiss, Zhilin Qu, Kalyanam Shivkumar

Abstract readReview
In one paragraph

Review in Heart rhythm, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Immune responses and activity of inflammatory mediators in pulmonary vein arrhythmogenesis.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Challenges Associated with Interpreting Mechanisms of AF.Arrhythmia & electrophysiology review · 2020
    Review
  7. Frontiers in physiology · 2020
    Article
  8. MulticellularFrontiers in cardiovascular medicine · 2020
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James N WeissUCLA Cardiovascular Research Laboratory. Electronic address: jweiss@mednet.ucla.edu.
Zhilin QuUCLA Cardiovascular Research Laboratory.
Kalyanam ShivkumarCardiac Arrhythmia Center & Neurocardiology Research Center of Excellence, Departments of Medicine (Cardiology) and Physiology, David Geffen School of Medicine, University of California, Los Angeles, California.

Funding

WAVE DYNAMICS IN NORMAL AND DISEASED RABBIT HEARTSP01HL078931 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOHN, SCOTT · 2005 to 2015
$20.7M
ELECTROPHYSIOLOGICAL EFFECTS OF NEURAL REMODELING OF THE VENTRICLESR01HL084261 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIVKUMAR, KALYANAM · 2006 to 2016
$3.4M
NHLBI NIH HHS P01 HL078931NHLBI NIH HHS R01 HL084261
6 · The paper itself

Abstract

Although considerable progress has been made in developing ablation approaches to cure atrial fibrillation (AF), outcomes are still suboptimal, especially for persistent and long-lasting persistent AF. In this topical review, we review the arrhythmia mechanisms, both reentrant and nonreentrant, that are potentially relevant to human AF at various stages/settings. We describe arrhythmia mapping techniques used to distinguish between the different mechanisms, with a particular focus on the detection of rotors. We discuss which arrhythmia mechanisms are likely to respond to ablation, and the challenges and prospects for improving upon current ablation strategies to achieve better outcomes.

Indexed as

Translational Research, BiomedicalAtrial FibrillationCatheter AblationHeart Conduction SystemHumansAblationArrhythmiaAtrial fibrillationAutomaticityFibrosisReentryRotorTriggered activity

Identifiers

PMID27241354
PMCPMC4996702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.