Evidence map›Paper›PMID 27240846›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2016

Is there a place for a biological mesh in perineal hernia repair?

G D Musters, O Lapid, J Stoker, B F Musters, W A Bemelman, P J Tanis

Open access · hybridAbstract read
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Perineal hernia repair: Multicentre comparative analysis of mesh-only versus mesh combined with tissue flap.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
  5. Laparoscopic perineal hernia repair after abdominoperineal resection.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  6. Review
  7. Surgical technique for primary perineal hernia repair: a systematic scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2023
    Article
  8. Article
  9. Review
  10. Quantifying displacement of urogenital organs after abdominoperineal resection for rectal cancer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021
    Article
  11. Article
  12. Further insights into the treatment of perineal hernia based on a the experience of a single tertiary centre.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2020
    Article
  13. Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

G D MustersDepartment of Surgery, Academic Medical Centre, University of Amsterdam, G4, Post box 22660, 1105 AZ, Amsterdam, The Netherlands.
O LapidDepartment of Plastic and Reconstructive Surgery, Academic Medical Centre, University of Amsterdam, G4, Post box 22660, 1105 AZ, Amsterdam, The Netherlands.
J StokerDepartment of Radiology, Academic Medical Centre, University of Amsterdam, Post box 22660, 1105 AZ, Amsterdam, The Netherlands.
B F MustersDepartment of Radiology, Medical Centre Alkmaar, Wilhelminalaan 12, 1815 JD, Alkmaar, The Netherlands.
W A BemelmanDepartment of Surgery, Academic Medical Centre, University of Amsterdam, G4, Post box 22660, 1105 AZ, Amsterdam, The Netherlands.
P J TanisDepartment of Surgery, Academic Medical Centre, University of Amsterdam, G4, Post box 22660, 1105 AZ, Amsterdam, The Netherlands. P.J.Tanis@amc.nl.
University of Amsterdam · NLMedisch Centrum Alkmaar · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to determine the outcome of perineal hernia repair with a biological mesh after abdominoperineal resection (APR).

methodAll consecutive patients who underwent perineal hernia repair with a porcine acellular dermal mesh between 2010 and 2014 were included. Follow-up was performed by clinical examination and MRI.

resultsFifteen patients underwent perineal hernia repair after a median of 25 months from APR. Four patients had a concomitant contaminated perineal defect, for which a gluteal fasciocutaneous flap was added in three patients. Wound infection occurred in three patients. After a median follow-up of 17 months (IQR 12-24), a clinically recurrent perineal hernia developed in 7 patients (47 %): 6 of 11 patients after a non-cross-linked mesh and 1 of 4 patients after a cross-linked mesh (p = 0.57). Routine MRI at a median of 17 months revealed a recurrent perineal hernia in 7 of 10 evaluable patients, with clinical confirmation of recurrence in 5 of these 7 patients. No recurrent hernia was observed in the three patients with combined flap reconstruction for contaminated perineal defects.

conclusionA high recurrence rate was observed after biological mesh repair of a perineal hernia following APR.

Indexed as

Acellular DermisBioprosthesisSurgical MeshAgedAnimalsFemaleHernia, AbdominalHerniorrhaphyHumansMaleMiddle AgedPerineumRectal NeoplasmsRecurrenceAbdominoperineal resectionBiological meshDynamic MRIHernia repairPerineal hernia

Identifiers

PMID27240846
PMCPMC5023741
OpenAlexW2419170923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.