ArticleInternational journal of health geographics2016
Agricultural crop exposure and risk of childhood cancer: new findings from a case-control study in Spain.
Article in International journal of health geographics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Passive environmental residential exposure to agricultural pesticides and hematological malignancies in the general population: a systematic review.Environmental science and pollution research international · 2021Pooled it
- Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies.International journal of cancer · 2026Article
- Causes of Childhood Cancer: A Literature Review (2014-2021)-Part 3: Environmental and Occupational Factors.Cancers · 2025Review
- Land use, zoning, and breast cancer incidence in California: an ecological study.Cancer causes & control : CCC · 2025Article
- Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina.Frontiers in toxicology · 2025Article
- Residential proximity to agricultural herbicide and fungicide applications and dust levels in homes of California children.Environment international · 2024Article
- Environmental Pollution and Risk of Childhood Cancer: A Scoping Review of Evidence from the Last Decade.International journal of molecular sciences · 2024Article
- Evaluating the accuracy of satellite-based methods to estimate residential proximity to agricultural crops.Journal of exposure science & environmental epidemiology · 2024Article
- Association between Residential Proximity to Viticultural Areas and Childhood Acute Leukemia Risk in Mainland France: GEOCAP Case-Control Study, 2006-2013.Environmental health perspectives · 2023Article
- Exploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence.International journal of environmental research and public health · 2023Article
- Residential proximity to croplands at birth and childhood leukaemia.Environmental health : a global access science source · 2022Article
- Article
- Exploring Blue Spaces' Effects on Childhood Leukaemia Incidence: A Population-Based Case-Control Study in Spain.International journal of environmental research and public health · 2022Article
- Beyond the map: evidencing the spatial dimension of health inequalities.International journal of health geographics · 2020Article
- Residential proximity to agriculture and risk of childhood leukemia and central nervous system tumors in the Danish national birth cohort.Environment international · 2020Article
- Crop proximity index for monitoring of peri-urban land use in agro-industrial crop regions.Heliyon · 2020Article
- Residential mobility in early childhood and the impact on misclassification in pesticide exposures.Environmental research · 2019Article
- Methodological approaches to the study of cancer risk in the vicinity of pollution sources: the experience of a population-based case-control study of childhood cancer.International journal of health geographics · 2019Article
- Using Watershed Boundaries to Map Adverse Health Outcomes: Examples From Nebraska, USA.Environmental health insights · 2018Article
- Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis.Environmental health : a global access science source · 2017Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildhood cancer is the main cause of disease-related death in children in Spain. Although little is known about the etiology, environmental factors are potential explanations for a fraction of the cases. Previous studies have shown pesticides to be associated with childhood cancer. The difficulty of collecting personal environmental exposure data is an important limitation; this lack of information about pesticides motivates the development of new methods to subrogate this exposure. We developed a crop exposure index based on geographic information to study the relationship between exposure to different types of crops and risk of childhood tumors.
methodsWe conducted a population-based case-control study of childhood cancer covering 3350 cases and 20,365 controls in two Spanish regions. We used CORINE Land Cover to obtain data about agricultural land use. We created a 1 km buffer around every child and calculated the percentage of crop surface within the buffer (Global Crop Index) for total crops and for individual types of crops. We fitted mixed multiple unconditional logistic regression models by diagnostic group.
resultsWe found excess of risk among children living in the proximity of crops. For total crops our results showed excesses of risk for almost all diagnostic groups and increasing risk with increasing crop index value. Analyses by region and individual type of crop also showed excess of risk.
conclusionThe results suggest that living in the proximity of cultivated land could be a risk factor for several types of cancer in children.
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