ArticleMolecular psychiatry2017
High-resolution copy number variation analysis of schizophrenia in Japan.
Abstract read
In one paragraph
Article in Molecular psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 136 citations in OpenAlex.
- Increased RHOA expression in peripheral blood mononuclear cells of patients with acute schizophrenia.Molecular biology reports · 2026Article
- A scoping review of genetic studies of treatment-resistant schizophrenia.Frontiers in genetics · 2026Review
- Whole-genome sequencing analysis of Japanese autism spectrum disorder trios.Psychiatry and clinical neurosciences · 2025Article
- Copy number variations in RNF216 and postsynaptic membrane-associated genes are associated with bipolar disorder: a case-control study in the Japanese population.Psychiatry and clinical neurosciences · 2025Article
- Treatment-resistant schizophrenia with 22q11.2 deletion and additional genetic defects.Neuropsychopharmacology reports · 2024Article
- Analysis of human neuronal cells carrying ASTN2 deletion associated with psychiatric disorders.Translational psychiatry · 2024Article
- Cohen syndrome combined with psychiatric symptoms: a case report.BMC psychiatry · 2024Article
- Association between copy number variations in parkin (PRKN) and schizophrenia and autism spectrum disorder: A case-control study.Neuropsychopharmacology reports · 2024Article
- Pleiotropic contribution of rbfox1 to psychiatric and neurodevelopmental phenotypes in two zebrafish models.Translational psychiatry · 2024Article
- Genomic and Reverse Translational Analysis Discloses a Role for Small GTPase RhoA Signaling in the Pathogenesis of Schizophrenia: Rho-Kinase as a Novel Drug Target.International journal of molecular sciences · 2023Review
- Pleiotropic contribution ofbioRxiv : the preprint server for biology · 2023Article
- Reelin Signaling in Neurodevelopmental Disorders and Neurodegenerative Diseases.Brain sciences · 2023Review
- Copy Number Variations in Neuropsychiatric Disorders.International journal of molecular sciences · 2023Review
- A Novel Genetic Variant inInternational journal of molecular sciences · 2023Article
- Different activity patterns control various stages of Reelin synthesis in the developing neocortex.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis.Schizophrenia bulletin · 2023Article
- Clinical characterization of patients with schizophrenia and 16p13.11 duplication: A case series.Neuropsychopharmacology reports · 2023Article
- Copy Number Variations and Schizophrenia.Molecular neurobiology · 2023Review
- Clinical manifestations of schizophrenia in four patients with variants in voltage-gated calcium channel-encoding genes: a case series.Psychiatry and clinical neurosciences · 2023Article
- Genome-scale copy number variant analysis in schizophrenia patients and controls from South India.Frontiers in molecular neuroscience · 2023Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
49 authors at 11 institutions in 2 countries.
I KushimaInstitute for Advanced Research, Nagoya University, Nagoya, Japan.
B AleksicDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0001-8982-4580
M NakatochiBioinformatics Section, Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.ORCID 0000-0002-1838-4837
T ShimamuraDivision of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
T ShiinoDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
A YoshimiDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
H KimuraDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Y TakasakiDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
C WangDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
J XingDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
K IshizukaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
T Oya-ItoDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0001-6921-4566
Y NakamuraDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Y AriokaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
T MaedaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
M YamamotoDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
M YoshidaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
H NomaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
S HamadaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
M MorikawaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Y UnoDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
T OkadaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
T IidakaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0002-6199-8711
S IritaniDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
T YamamotoDepartment of Legal Medicine and Bioethics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
M MiyashitaDepartment of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
A KoboriDepartment of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
M AraiDepartment of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
M ItokawaCenter for Medical Cooperation, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
M-C ChengDepartment of Psychiatry, Yuli Mental Health Research Center, Yuli Branch, Taipei Veterans General Hospital, Hualien, Taiwan.
Y-A ChuangDepartment of Psychiatry, Yuli Mental Health Research Center, Yuli Branch, Taipei Veterans General Hospital, Hualien, Taiwan.
C-H ChenDepartment of Psychiatry, Chang Gung Memorial Hospital-Linkou, Taoyuan, Taiwan.
M SuzukiDepartment of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan.
T TakahashiDepartment of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan.
R HashimotoMolecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Suita, Japan.ORCID 0000-0002-5941-4238
H YamamoriDepartment of Psychiatry, Osaka University Graduate School of Medicine, Suita, Japan.
Y YasudaDepartment of Psychiatry, Osaka University Graduate School of Medicine, Suita, Japan.
Y WatanabeDepartment of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
A NunokawaDepartment of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
T SomeyaDepartment of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
M IkedaDepartment of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
T ToyotaLaboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan.
T YoshikawaLaboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Japan.
S NumataDepartment of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
T OhmoriDepartment of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
S KunimotoDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
D MoriDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
N IwataDepartment of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
N OzakiDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPTokyo Metropolitan Institute of Medical Science · JPNagoya University Hospital · JPNiigata University · JPThe University of Osaka · JPFujita Health University · JPRIKEN Center for Brain Science · JPTaipei Veterans General Hospital · TWTokushima University · JPUniversity of Toyama · JPChang Gung University · TW
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent schizophrenia (SCZ) studies have reported an increased burden of de novo copy number variants (CNVs) and identified specific high-risk CNVs, although with variable phenotype expressivity. However, the pathogenesis of SCZ has not been fully elucidated. Using array comparative genomic hybridization, we performed a high-resolution genome-wide CNV analysis on a mainly (92%) Japanese population (1699 SCZ cases and 824 controls) and identified 7066 rare CNVs, 70.0% of which were small (<100 kb). Clinically significant CNVs were significantly more frequent in cases than in controls (odds ratio=3.04, P=9.3 × 10
Indexed as
AdultCase-Control StudiesComparative Genomic HybridizationDNA Copy Number VariationsFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansJapanMalePolymorphism, Single NucleotideSchizophrenia
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.