Evidence map›Paper›PMID 27240405›Full record

ReviewGenes2016

Wool Keratin-Associated Protein Genes in Sheep-A Review.

Hua Gong, Huitong Zhou, Rachel H J Forrest, Shaobin Li, Jiqing Wang, Jolon M Dyer, Yuzhu Luo, Jon G H Hickford

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 115 citations in OpenAlex.

  1. Association ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Polymorphism of Keratin GeneAnimals : an open access journal from MDPI · 2025
    Article
  9. Article
  10. Variation in OvineAnimals : an open access journal from MDPI · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Characterisation of OvineAnimals : an open access journal from MDPI · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hua GongInternational Wool Research Institute, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China. gonghua3000@gmail.com.
Huitong ZhouInternational Wool Research Institute, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China. zhouh@lincoln.ac.nz.
Rachel H J ForrestFaculty of Health and Sport Sciences, Eastern Institute of Technology, Private Bag 1201, Napier 4142, New Zealand. rforrest@eit.ac.nz.
Shaobin LiInternational Wool Research Institute, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China. lisb@gsau.edu.cn.
Jiqing WangInternational Wool Research Institute, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China. wangjq@gsau.edu.cn.
Jolon M DyerFood & Bio-Based Products, Lincoln Research Centre, AgResearch Limited, Lincoln 7608, New Zealand. dyerj@agresearch.co.nz.
Yuzhu LuoInternational Wool Research Institute, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China. yzluo@gsau.edu.cn.
Jon G H HickfordInternational Wool Research Institute, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China. jon.hickford@lincoln.ac.nz.
Gansu Agricultural University · CNAgResearch · NZEastern Institute of Technology · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of sheep's wool in making textiles has inspired extensive research into its structure and the underlying genetics since the 1960s. Wool keratin-associated proteins (KAPs) are a key structural component of the wool fibre. The characterisation of the genes encoding these proteins has progressed rapidly with advances in the nucleotide and protein sequencing. This review describes our knowledge of ovine KAPs, their categorisation into families, polymorphism in the proteins and genes, the clustering and chromosomal location of the genes, some characteristics of gene expression and some potential effects of the KAPs on wool traits. The extent and nature of genetic variation in wool KAP genes and its association with fibre characteristics, provides an opportunity for the development of gene-markers for selective breeding of sheep to produce better wool with properties highly matched to specific end-uses.

Indexed as

expressionKeratin-associated protein (KAP)polymorphismsheepwool fibrewool traits

Identifiers

PMID27240405
PMCPMC4929423
OpenAlexW2395447748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.