ReviewAllergy2016
Microbiome and its impact on gastrointestinal atopy.
Review in Allergy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Eosinophilic esophagitis in children and adolescents: a clinical practice guideline.Italian journal of pediatrics · 2025Guideline
- Dietary composition of adult eosinophilic esophagitis patients is related to disease severity.Immunity, inflammation and disease · 2024Trial
- PHAGE Study: Effects of Supplemental Bacteriophage Intake on Inflammation and Gut Microbiota in Healthy Adults.Nutrients · 2019Trial
- Parasites and allergies: a complex bidirectional relationship from evolutionary origins to modern therapeutics.Antonie van Leeuwenhoek · 2026Review
- Aluminium ammonium sulphate induces epithelial pyroptosis and eosinophilic inflammation under dysbiotic conditions: ameliorative effects of heparin.Cell death discovery · 2026Article
- The microbiome in mind: Reflections on antibiotic prescription in primary care.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025Article
- Tumor necrosis factor receptor 2 in allergen tolerance: a perspective view.Frontiers in immunology · 2025Review
- Eosinophilic Esophagitis and Inflammatory Bowel Disease: What Are the Differences?International journal of molecular sciences · 2024Review
- Epidemiologic and Clinical Clues to the Etiology of Eosinophilic Esophagitis.Immunology and allergy clinics of North America · 2024Review
- Review article: Emerging insights into the epidemiology, pathophysiology, diagnostic and therapeutic aspects of eosinophilic oesophagitis and other eosinophilic gastrointestinal diseases.Alimentary pharmacology & therapeutics · 2024Review
- Behaviour and sun exposure in holidaymakers alters skin microbiota composition and diversity.Frontiers in aging · 2023Article
- Nature with Nurture: the Role of Intrinsic Genetic and Extrinsic Environmental Factors on Eosinophilic Esophagitis.Current allergy and asthma reports · 2022Review
- Comprehensive Analysis of the Structure and Allergenicity Changes of Seafood Allergens Induced by Non-Thermal Processing: A Review.Molecules (Basel, Switzerland) · 2022Review
- The Microbiota-Bone-Allergy Interplay.International journal of environmental research and public health · 2021Review
- Eosinophilic Esophagitis: A Review.JAMA · 2021Review
- Effect of topical swallowed steroids on the bacterial and fungal esophageal microbiota in eosinophilic esophagitis.Allergy · 2021Article
- Early life factors are associated with risk for eosinophilic esophagitis diagnosed in adulthood.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2021Article
- Efficacy of Probiotics in Children and Adolescents With Atopic Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Study.Frontiers in nutrition · 2021Article
- Bacteriophages in food supplements obtained from natural sources.Acta bio-medica : Atenei Parmensis · 2020Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The prevalence of allergic conditions has continuously increased in the last few decades in Westernized countries. A dysbiotic gut microbiome may play an important role in the development of allergic diseases. Genetic, environmental, and dietary factors may alter the commensal microbiota leading to inflammatory dysregulation of homeostasis. Murine and human studies have begun to elucidate the role of the microbiota in the pathogenesis of atopic diseases including asthma, atopic dermatitis, and food allergies. However, the role of the microbiome in most eosinophilic gastrointestinal diseases (EGIDs) is not yet known. This review provides an overview of what is currently known about the development of tolerance from both molecular and clinical standpoints. We also look at the gut-specific microbiome and its role in atopic conditions with the hope of applying this knowledge to the understanding, prevention, and treatment of EGIDs, particularly EoE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.