ArticlePsycho-oncology2017
Cancer negatively impacts on sexual function in adolescents and young adults: The AYA HOPE study.
Article in Psycho-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The effect of whatsapp based ex-plissit model sexual counseling on sexual function and sexual distress in breast cancer survivors: a randomized controlled study
Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians: ReSPECT Intervention Proof-of-Concept Testing
Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- Technology-Assisted Psychosocial Interventions for Childhood, Adolescent, and Young Adult Cancer Survivors: A Systematic Review and Meta-Analysis.Journal of adolescent and young adult oncology · 2022Pooled it
- Unmet needs in sexual health in bladder cancer patients: a systematic review of the evidence.BMC urology · 2020Pooled it
- Sexual function in adolescents and young adults diagnosed with cancer: A systematic review.Journal of cancer survivorship : research and practice · 2018Pooled it
- The role of a discussion forum within a web-based psychoeducational intervention focusing on sex and fertility-What do young adults communicate?Cancer medicine · 2023Trial
- Body esteem and sexual life in Turkish patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Appraisal of sexual functioning before and after cancer: insights from adolescent and young adult (AYA) cancer survivors and matched healthy controls.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Provider-Engaged Development of a Sexual Dysfunction Screening Approach for Adolescents and Young Adult Childhood Cancer Survivors: Iterative Co-Design Study.JMIR formative research · 2026Article
- Exploration of the relevance and comprehensibility of the European Organization for the Research and Treatment of Cancer Sexual Health Questionnaire among Danish young adults aged 18-39: a national cross-sectional study.Journal of patient-reported outcomes · 2025Article
- Informed and Empowered: A Pre-Post Evaluation of a Whiteboard Video for Sexual Health Education in Female Adolescents and Young Adults with Cancer.Current oncology (Toronto, Ont.) · 2025Article
- Proton Beam Therapy and the AYA Sarcoma Patient Journey: Highlighting Needs from Diagnosis to Survivorship.Cancers · 2025Review
- Survivorship Considerations and Management in the Adolescent and Young Adult Sarcoma Population: A Review.Current oncology (Toronto, Ont.) · 2025Review
- Understanding the impact of early onset colorectal cancer on quality of life: a qualitative analysis of online forum data.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Bridging gaps in cancer care for young adults: A collaborative e-learning initiative for oncology nurses.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2025Article
- Experiences Using Nonpharmacological Interventions for Chronic Fatigue: A Focus Group Study of Long-Term Survivors of Young Adult Cancers With Fatigue.Cancer reports (Hoboken, N.J.) · 2024Article
- Testing effectiveness and implementation of a standardized approach to sexual dysfunction screening among adolescent and young adult-aged survivors of childhood cancer: A type I hybrid, mixed methods trial protocol: Effectiveness of sexual dysfunction screening among AYA cancer survivors: a study protocol.medRxiv : the preprint server for health sciences · 2024Article
- Sexuality, intimacy, and body image among adolescents and young adults with cancer: a qualitative, explorative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Health Care Transitions Among Adolescents and Young Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Review
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- Healthcare Professional Communication on Sexual Health: A Report from the Italian Working Group on Adolescents and Young Adults with Cancer.The oncologist · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 8 institutions in 2 countries.
Funding
Abstract
objectiveThis cohort study examined the impact of cancer on sexual function and intimate relationships in adolescents and young adults (AYAs). We also explored factors predicting an increased likelihood that cancer had negatively affected these outcomes.
methodsParticipants (n = 465, ages 15-39) in the Adolescent and Young Adult Health Outcomes and Patient Experience (AYA HOPE) study completed two surveys approximately 1 and 2 years post-cancer diagnosis. We used multivariable logistic regression to determine factors negatively affected by perceptions of sexual function at 2 years post-diagnosis.
resultsForty-nine percent of AYAs reported negative effects on sexual function at 1 year post-cancer diagnosis and 70% of those persisted in their negative perceptions 2 years after diagnosis. Those reporting a negative impact at 2 years were more likely to be 25 years or older (OR, 2.53; 95% CI, 1.44-4.42), currently not raising children (OR, 1.81; 95% CI, 1.06-3.08), experiencing fatigue (OR, 0.99; 95% CI, 0.975-0.998) and more likely to report that their diagnosis has had a negative effect on physical appearance (OR, 3.08; 95% CI, 1.97-4.81). Clinical factors and mental health were not significant predictors of negative effects on sexual function.
conclusionsMany AYAs diagnosed with cancer experience a persistent negative impact on sexual life up to 2 years following diagnosis. The findings underscore the need to develop routine protocols to assess sexual function in AYAs with cancer and to provide comprehensive management in the clinical setting. Copyright © 2016 John Wiley & Sons, Ltd.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.