Evidence map›Paper›PMID 27239956›Full record

ArticleInfluenza and other respiratory viruses2016

Sentinel surveillance for influenza among severe acute respiratory infection and acute febrile illness inpatients at three hospitals in Ghana.

Alexander H Jones, William Ampofo, Richard Akuffo, Brooke Doman, Christopher Duplessis, Joseph A Amankwa, Charity Sarpong, Ken Sagoe, Prince Agbenohevi, Naiki Puplampu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  11. Strengthening laboratory surveillance of viral pathogens: Experiences and lessons learned building next-generation sequencing capacity in Ghana.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019
    Article
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Burden of influenza among hospitalized febrile children in Ghana.Influenza and other respiratory viruses · 2017
    Article
  18. Article
  19. Is there Co-infection of Influenza and Covid-19 in Jos, North Central Nigeria?Nigerian medical journal : journal of the Nigeria Medical Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Alexander H JonesGlobal Disease Detection and Response Program, U.S. Naval Medical Research Unit No. 3, Cairo, Egypt.
William AmpofoNoguchi Memorial Institute for Medical Research, National Influenza Center, Accra, Ghana.
Richard AkuffoGlobal Disease Detection and Response Program, U.S. Naval Medical Research Unit No. 3 Ghana Detachment, Accra, Ghana.
Brooke DomanGlobal Disease Detection and Response Program, U.S. Naval Medical Research Unit No. 3 Ghana Detachment, Accra, Ghana.
Christopher DuplessisU.S. Naval Medical Research Unit No. 3 Ghana Detachment, Accra, Ghana.
Joseph A AmankwaGhana Health Service, Accra, Ghana.
Charity SarpongGhana Health Service, Accra, Ghana.
Ken SagoeTamale Teaching Hospital, Tamale, Ghana.
Prince Agbenohevi37 Military Hospital, Accra, Ghana.
Naiki PuplampuU.S. Naval Medical Research Unit No. 3 Ghana Detachment, Accra, Ghana.
George ArmahNoguchi Memorial Institute for Medical Research, Accra, Ghana.
Kwadwo A KoramNoguchi Memorial Institute for Medical Research, Accra, Ghana.
Edward O Nyarko37 Military Hospital, Accra, Ghana.
Samuel Bel-Nono37 Military Hospital, Accra, Ghana.
Erica L DuegerU.S. Centers for Disease Control & Prevention, Atlanta, GA, USA.
37 Military Hospital · GHNoguchi Memorial Institute for Medical Research · GHGhana Health Service · GHNaval Medical Research Command · USNaval Medical Research Unit Six · PEUnited States Naval Medical Research Unit III · EGTamale Teaching Hospital · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza epidemiology in Africa is generally not well understood. Using syndrome definitions to screen patients for laboratory confirmation of infection is an established means to effectively conduct influenza surveillance.

methodsTo compare influenza-related epidemiologic data, from October 2010 through March 2013, we enrolled hospitalized severe acute respiratory infection (SARI; fever with respiratory symptoms) and acute febrile illness (AFI; fever without respiratory or other localizing symptoms) patients from three referral hospitals in Ghana. Demographic and epidemiologic data were obtained from enrolled patients after which nasopharyngeal and oropharyngeal swabs were collected, and processed by molecular methods for the presence of influenza viruses.

resultsOf 730 SARI patients, 59 (8%) were influenza positive; of 543 AFI patients, 34 (6%) were positive for influenza. Both SARI and AFI surveillance yielded influenza A(H3N2) (3% versus 1%), A(H1N1)pdm09 (2% versus 1%), and influenza B (3% versus 4%) in similar proportions. Data from both syndromes show year-round influenza transmission but with increased caseloads associated with the rainy seasons.

conclusionsAs an appreciable percentage of influenza cases (37%) presented without defined respiratory symptoms, and thus met the AFI but not the SARI definition, it is important to consider broader screening criteria (i.e., AFI) to identify all laboratory-confirmed influenza. The identified influenza transmission seasonality has important implications for the timing of related public health interventions.

Indexed as

InpatientsSentinel SurveillanceAcute DiseaseAdolescentAdultChildChild, PreschoolFemaleFeverGhanaHospitalizationHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanMaleGhanahumaninfluenzasentinel surveillance

Identifiers

PMID27239956
PMCPMC4947945
OpenAlexW2412064398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.