ReviewJournal of current ophthalmology2016
Erythropoietin in ophthalmology: A literature review.
Review in Journal of current ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Combination of intravitreal bevacizumab and erythropoietin versus intravitreal bevacizumab alone for refractory diabetic macular edema: a randomized double-blind clinical trial.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Trial
- Therapeutic Approaches for Toxic Optic Neuropathies: Insights from Methanol-Induced Optic Neuropathy and NAION Treatments.Diagnostics (Basel, Switzerland) · 2025Review
- Antioxidant Molecules in the Human Vitreous Body During Prenatal Eye Development.Antioxidants (Basel, Switzerland) · 2025Review
- Delayed reversal of methanol-induced blindness in an adult by a combination of erythropoietin and a high dose of methylprednisolone: a case report.Journal of medical case reports · 2023Article
- Intravenous plus intravitreal erythropoietin for management of methanol toxicity optic neuropathy: A case report and brief review.Clinical case reports · 2023Article
- Porcine Corneas Incubated at Low Humidity Present Characteristic Features Found in Dry Eye Disease.International journal of molecular sciences · 2022Article
- Chitosan and Hyaluronic Acid Nanoparticles as Vehicles of Epoetin Beta for Subconjunctival Ocular Delivery.Marine drugs · 2022Article
- Erythropoietin in Lupus: Unanticipated Immune Modulating Effects of a Kidney Hormone.Frontiers in immunology · 2021Review
- Article
- Serum erythropoietin concentration and its correlation with stage of diabetic retinopathy.BMC ophthalmology · 2019Article
- Time-dependent changes in hypoxia- and gliosis-related factors in experimental diabetic retinopathy.Eye (London, England) · 2019Article
- Intravitreal erythropoietin injection in late-stage optic neuropathy: a safety study on human.International ophthalmology · 2018Article
- Neuroprotective effects of erythropoietin on rat retinas subjected to oligemia.Clinics (Sao Paulo, Brazil) · 2018Article
- Visual-Evoked-Response-Supported Outcome of Intravitreal Erythropoietin in Management of Indirect Traumatic Optic Neuropathy.Journal of ophthalmology · 2018Article
- Ex vivo permeation of erythropoietin through porcine conjunctiva, cornea, and sclera.Drug delivery and translational research · 2017Article
- Association between macular degeneration and mild to moderate chronic kidney disease: A nationwide population-based study.Medicine · 2017Observational
- Erythropoietin promoted the proliferation of hepatocellular carcinoma through hypoxia induced translocation of its specific receptor.Cancer cell international · 2017Article
- Functional and Structural Effects of Erythropoietin Subconjunctival Administration in Glaucomatous Animals.Biomedicine hubArticle
- Visual outcome of methanol toxic optic neuropathy after erythropoietin treatment in Riyadh, Saudi Arabia.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- Visual Outcomes of Adding Erythropoietin to Methylprednisolone for Treatment of Retrobulbar Optic Neuritis.Journal of ophthalmic & vision researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the current literature on ocular application of erythropoietin (EPO).
methodsA comprehensive search was performed on Pubmed and Scopus databases. All selected articles were reviewed thoroughly by the authors to review current applications of the EPO in ocular diseases.
resultsVarious aspects of administration of EPO for different ischemic, traumatic, vascular, and degenerative disorders have been explained. The articles are generally preclinical with few small studies reporting clinical outcomes.
conclusionEPO has been used for the treatment of different ophthalmic conditions with promising results. Further studies are needed to elaborate the role of EPO in management of ocular diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.