Evidence map›Paper›PMID 27239560›Full record

ArticleJSM cell & developmental biology

Platelet-Activating Factor-Receptor and Tumor Immunity.

Ravi P Sahu, Raymond L Konger, Jeffrey B Travers

Abstract read
In one paragraph

Article in JSM cell & developmental biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. MicroRNA heterogeneity in melanoma progression.Seminars in cancer biology · 2019
    Review
  4. MicroRNA-Directed Cancer Therapies: Implications in Melanoma Intervention.The Journal of pharmacology and experimental therapeutics · 2018
    Review
  5. Article
  6. Implications of Aspirin for Melanoma Treatment: A Short Perspective.Journal of molecular genetics and medicine · 2017
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ravi P SahuDepartment of Pathology & Laboratory Medicine, Indiana University School of Medicine, USA; Department of Dermatology, Indiana University School of Medicine, USA.
Raymond L KongerDepartment of Pathology & Laboratory Medicine, Indiana University School of Medicine, USA; Department of Dermatology, Indiana University School of Medicine, USA.
Jeffrey B TraversDepartment of Pathology & Laboratory Medicine, Indiana University School of Medicine, USA; Department of Pharmacology and Toxicology, Indiana University School of Medicine, USA; Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, USA.

Funding

Platelet Activating Factor and Epidermic CytotoxicityR01HL062996 · NHLBI · WRIGHT STATE UNIVERSITY · PI TRAVERS, JEFFREY B. · 1999 to 2023
$7.2M
Environmental pro-oxidative stressors and immunosuppressionK22ES023850 · NIEHS · WRIGHT STATE UNIVERSITY · PI SAHU, RAVI PRAKASH · 2014 to 2016
$488k
Oxidized Lipids and UV ImmunosuppressionI01BX000853 · VA · RLR VA MEDICAL CENTER · PI Jeffrey B. Travers · 2011 to 2026
–
BLRD VA I01 BX000853NHLBI NIH HHS R01 HL062996NIEHS NIH HHS K22 ES023850
6 · The paper itself

Abstract

First described in 1972 by Benveniste and colleagues, platelet-activating factor (PAF) remains one of the potent phospholipid known to date. The role of PAF produced enzymatically in mediating diverse biological and pathophysiological processes including inflammatory and allergic diseases and cancers in response to various stimuli has been extensively studied. However, little is known about the role of non-enzymatically-generated PAF-like lipids produced in response to pro-oxidative stressors, particularly in modulating the host immune responses to tumor immunity, which is the focus of this review.

Identifiers

PMID27239560
PMCPMC4880409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.