Evidence map›Paper›PMID 27239559›Full record

ArticleAIMS biophysics

STIM1 activation is regulated by a 14 amino acid sequence adjacent to the CRAC activation domain.

Marek K Korzeniowski, Barbara Baird, David Holowka

Open access · goldAbstract read
In one paragraph

Article in AIMS biophysics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Alpha synuclein modulates mitochondrial CaNPJ Parkinson's disease · 2023
    Article
  3. Alpha Synuclein Modulates Mitochondrial CabioRxiv : the preprint server for biology · 2023
    Article
  4. Review
  5. Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines.Pflugers Archiv : European journal of physiology · 2018
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marek K KorzeniowskiDepartment of Chemistry and Chemical Biology Cornell University, Ithaca, NY 14853.
Barbara BairdDepartment of Chemistry and Chemical Biology Cornell University, Ithaca, NY 14853.
David HolowkaDepartment of Chemistry and Chemical Biology Cornell University, Ithaca, NY 14853.
Cornell University · US

Funding

INTERACTIVE STRUCTURES AND DYNAMICS OF ANTIGEN RECEPTORSR01AI022449 · NIAID · CORNELL UNIVERSITY ITHACA · PI HOLOWKA, DAVID A · 1985 to 2014
$3.6M
High Resolution Characterization of Receptor Signaling and RegulationR01GM117552 · NIGMS · CORNELL UNIVERSITY · PI BAIRD, BARBARA A, HOLOWKA, DAVID A · 2016 to 2023
$3.2M
NIAID NIH HHS R01 AI022449NIGMS NIH HHS R01 GM117552
6 · The paper itself

Abstract

Oligomerization of the Ca

Indexed as

cell signalingconformational changeCRAC channel protein1 (ORAI1)endoplasmic reticulum (ER)fluorescence resonance energy transfer (FRET)membrane functionstromal interaction molecule 1 (STIM1)

Identifiers

PMID27239559
PMCPMC4883682
OpenAlexW2280398043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.