ArticleJournal of cachexia, sarcopenia and muscle2016
Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi-continent study.
Article in Journal of cachexia, sarcopenia and muscle, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03343886 (Ageing and Health. Spanish Longitudinal Study on Ageing, Physical and Mental Health, and Its Determinants), which is not on this map. Cited by 148 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ageing and Health. Spanish Longitudinal Study on Ageing, Physical and Mental Health, and Its Determinants
Who cites it
148 citing papers in PubMed, 4 syntheses or guidelines pooled it, 286 citations in OpenAlex.
- The Effects of SGLT2 Inhibitors on Muscle Health in Older Adults: A Systematic Review and Meta-Analysis.Pharmacology research & perspectives · 2026Pooled it
- Prevalence of sarcopenic obesity in the older non-hospitalized population: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Associated Factors of Sarcopenia in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- The Prevalence of Sarcopenia in Chinese Older Adults: Meta-Analysis and Meta-Regression.Nutrients · 2021Pooled it
- A cross-sectional study about the relationship between physical activity and sarcopenia in Taiwanese older adults.Scientific reports · 2021Trial
- Review
- Muscle-Adipose Aging Dynamics and Inflammaging Patterns Across Ethnically Diverse Populations: Exploring Potential Roles of Lipolysis.Journal of cachexia, sarcopenia and muscle · 2026Article
- Social isolation and sarcopenia: the mediating role of physical activity and the intersocietal differences from US and China.Social psychiatry and psychiatric epidemiology · 2026Article
- Frailty and Sarcopenia in Elderly Diabetes Mellitus.Journal of clinical medicine · 2026Article
- Trends in Low Muscle Mass and Sarcopenia Prevalence in Korea Using Korea National Health and Nutrition Examination Survey (KNHANES) 2024 and 2008-2011: The KSBMR-KSOS KNHANES DXA Joint Task Force Report.Journal of bone metabolism · 2026Article
- Normative data and standardized scores for sarcopenia indicators in middle-aged and older adults: a large screening-based cohort study.Osteoporosis and sarcopenia · 2026Article
- Physical Activity Types and Sarcopenia Components Among Middle-Aged and Older People: A Cross-Sectional Study.Calcified tissue international · 2026Article
- Comparative Effects of Weighted Vest and Whole-Body Vibration Training on Bone and Muscle Health in Osteopenia.Life (Basel, Switzerland) · 2026Article
- Article
- Diagnostic variability in sarcopenia and sarcopenic obesity among older adults: a clinical and public health challenge.Frontiers in nutrition · 2026Article
- Sarcopenia with postoperative outcomes in patients undergoing pancreaticoduodenectomy.Bioinformation · 2026Article
- Osteosarcopenic obesity and the progression of physical frailty, cognition function, and mental health: First longitudinal evidence from ELSA.The journal of nutrition, health & aging · 2026Article
- Sarcopenia in the Aging Process: Pathophysiological Mechanisms, Clinical Implications, and Emerging Therapeutic Approaches.International journal of molecular sciences · 2025Review
- Long-term effect of physical inactivity on osteosarcopenic obesity - a MRI-based investigation from a population-based cohort.BMC musculoskeletal disorders · 2025Observational
- Osteosarcopenia as a risk factor for depression: Longitudinal findings from the SHARE study.Bone reports · 2025Article
88 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 5 countries.
Funding
Abstract
backgroundThe aim of this study was to evaluate the factors associated with low skeletal muscle mass (SMM), sarcopenia, and sarcopenic obesity using nationally representative samples of people aged ≥65 years from diverse geographical regions of the world.
methodsData were available for 18 363 people aged ≥65 years who participated in the Collaborative Research on Ageing in Europe survey conducted in Finland, Poland, and Spain, and the World Health Organization Study on global AGEing and adult health survey conducted in China, Ghana, India, Mexico, Russia, and South Africa, between 2007 and 2012. A skeletal muscle mass index (SMI) was created to reflect SMM. SMM, SMI, and percent body fat (%BF) were calculated with specific indirect population formulas. These estimates were based on age, sex, weight, height, and race. Sarcopenia and sarcopenic obesity were defined with specific cut-offs.
resultsThe prevalence of sarcopenia ranged from 12.6% (Poland) to 17.5% (India), and that of sarcopenic obesity ranged from 1.3% (India) to 11.0% (Spain). Higher %BF was associated with lower SMM in all countries, and with sarcopenia in five countries (p < 0.001). Compared to high levels of physical activity, low levels were related with higher odds for sarcopenia [OR 1.36 (95%CI 1.11-1.67)] and sarcopenic obesity [OR 1.80 (95%CI 1.23-2.64)] in the overall sample. Also, a dose-dependent association between higher numbers of chronic diseases and sarcopenic obesity was observed.
conclusionsPhysical activity and body composition changes such as high %BF are key factors for the prevention of sarcopenia syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.