ReviewJournal of cachexia, sarcopenia and muscle2016
Adiponectin resistance in skeletal muscle: pathophysiological implications in chronic heart failure.
Review in Journal of cachexia, sarcopenia and muscle, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Nutritional interventions for heart failure patients who are malnourished or at risk of malnutrition or cachexia: a systematic review and meta-analysis.Heart failure reviews · 2021Pooled it
- Impact of SGLT2 ınhibitors on nutritional and ımmunologic status in chronic heart failure.BMC cardiovascular disorders · 2026Observational
- Imaging and biomarker-based risk stratification in TAVI: the role of epicardial fat, visceral fat, and adiponectin.European heart journal open · 2026Article
- Muscle ultrasound in heart failure: pathophysiological profiling and clinical stratification.Internal and emergency medicine · 2026Review
- Early metabolic predictors of type 2 diabetes mellitus in normoglycemic adults: insights from six-year prospective cohort study.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Integrin Trafficking, Fibronectin Architecture, and Glomerular Injury upon Adiponectin Receptor 1 Depletion.Journal of the American Society of Nephrology : JASN · 2025Article
- Correlation between blood cell indices and adiponectin and leptin levels in COVID-19.Biomolecules & biomedicine · 2025Article
- Review
- Controlling the nutritional status score: a new tool for predicting postoperative mortality in patients with infrarenal abdominal aortic aneurysm treated with endovascular aneurysm repair.Frontiers in nutrition · 2024Article
- Adiponectin Resistance in Obesity: Adiponectin Leptin/Insulin Interaction.Advances in experimental medicine and biology · 2024Review
- Regulation of cardiovascular health and disease by visceral adipose tissue-derived metabolic hormones.The Journal of physiology · 2023Article
- Body composition and sexual hormones for the glucose control of autoimmune diabetes in males: are they necessary to predict diabetes-related complications?Frontiers in endocrinology · 2023Article
- The crosstalk between BAT thermogenesis and skeletal muscle dysfunction.Frontiers in physiology · 2023Review
- Hyperlipidemic plasma molecules bind and inhibit adiponectin activity.Journal of diabetes investigation · 2022Article
- The gut microbiome as mediator between diet and its impact on immune function.Scientific reports · 2022Article
- The roles of epicardial adipose tissue in heart failure.Heart failure reviews · 2022Review
- Central Adiponectin Signaling - A Metabolic Regulator in Support of Brain Plasticity.Brain plasticity (Amsterdam, Netherlands) · 2022Review
- Microbiome Medicine: Microbiota in Development and Management of Cardiovascular Diseases.Endocrine, metabolic & immune disorders drug targets · 2022Review
- Reconsideration of Alzheimer's Disease Therapy from a Viewpoint of Amyloidogenic Evolvability.Journal of Alzheimer's disease reports · 2022Article
- Impact of weight loss in patients with heart failure with preserved ejection fraction: results from the FLAGSHIP study.ESC heart failure · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal muscle wasting is a common complication of chronic heart failure (CHF) and linked to poor patient prognosis. In recent years, adiponectin was postulated to be centrally involved in CHF-associated metabolic failure and muscle wasting. This review discusses current knowledge on the role of adiponectin in CHF. Particular emphasis will be given to the complex interaction mechanisms and the intracellular pathways underlying adiponectin resistance in skeletal muscle of CHF patients. In this review, we propose that the resistance process is multifactorial, integrating abnormalities emanating from insulin signalling, mitochondrial biogenesis, and ceramide metabolism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.