Evidence map›Paper›PMID 27239390›Full record

ArticleOpen journal of biophysics2015

Free Volume in Membranes: Viscosity or Tension?

V S Markin, F Sachs

Abstract read
In one paragraph

Article in Open journal of biophysics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Piezo1: the key regulators in central nervous system diseases.Frontiers in cellular neuroscience · 2024
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Asymmetric mechanosensitivity in a eukaryotic ion channel.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Free Volume in Membranes: Viscosity or Tension?Open journal of biophysics · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

V S MarkinDepartment of Anesthesiology and Pain Management, UT Southwestern, Dallas, TX, USA.
F SachsPhysiology & Biophysical Sciences, SUNY Buffalo, Buffalo, NY, USA.

Funding

Mechanosensitive ion channels and cortical mechanicsR01HL054887 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI SACHS, FREDERICK · 1995 to 2016
$9.6M
NHLBI NIH HHS R01 HL054887
6 · The paper itself

Abstract

Many papers have used fluorescent probe diffusion to infer membrane viscosity but the measurement is actually an assay of the free volume of the membrane. The free volume is also related to the membrane tension. Thus, changes in probe mobility refer equally well to changes in membrane tension. In complicated structures like cell membranes, it appears more intuitive to consider variations in free volume as referring to the effect of domains structures and interactions with the cytoskeleton than changes in viscosity since tension is a state variable and viscosity is not.

Indexed as

AnisotropyBilayerFluorescenceLipidPolarization

Identifiers

PMID27239390
PMCPMC4882100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.