ArticleJournal of animal science and biotechnology2016
Effects of benzoic acid (VevoVitall®) on the performance and jejunal digestive physiology in young pigs.
Article in Journal of animal science and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 79 citations in OpenAlex.
- Effects of Compound Yeast Culture on the Intestinal Morphology, Intestinal Function, and Microorganisms of Weaned Lambs.Probiotics and antimicrobial proteins · 2026Article
- Benzoic acid decreases biological value of nitrogen without affecting nitrogen retention in nursery pigs fed crude protein-limited diets.Journal of animal science · 2026Article
- Effects of different acidifiers on the growth performance and diarrhea score of weaned piglets under commercial pig farm conditions.Translational animal science · 2026Article
- Benzoic acid-the cornerstone of any swine nutrition program.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- Effect of Benzoic Acid on Nutrient Digestibility and Rectal Microbiota of Weaned Holstein Dairy Calves.Animals : an open access journal from MDPI · 2025Article
- Optimising Nutrition for Sustainable Pig Production: Strategies to Quantify and Mitigate Environmental Impact.Animals : an open access journal from MDPI · 2025Review
- Benzoic acid supplementation in crude protein-deficient diets reduces nursery pig growth performance.Journal of animal science · 2025Article
- Effects of benzoic acid in pig diets on nitrogen utilization, urinary pH, slurry pH, and odorous compounds.Animal bioscience · 2024Article
- Plasma metabolomic characteristics of atrial fibrillation patients with spontaneous echo contrast.BMC cardiovascular disorders · 2024Article
- Effect of Dietary Benzoic Acid Supplementation on Growth Performance, Rumen Fermentation, and Rumen Microbiota in Weaned Holstein Dairy Calves.Animals : an open access journal from MDPI · 2024Article
- Protective Effect of Coated Benzoic Acid on Intestinal Epithelium in Weaned Pigs upon EnterotoxigenicAnimals : an open access journal from MDPI · 2024Article
- Dietary Intervention of Benzoic Acid for Intestinal Health and Growth of Nursery Pigs.Animals : an open access journal from MDPI · 2024Review
- Effects of single and complex probiotics in growing-finishing pigs and swine compost.Journal of animal science and technology · 2024Article
- Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.Journal of animal science and biotechnology · 2024Article
- Effect of an organic acid blend as an antibiotic alternative on growth performance, antioxidant capacity, intestinal barrier function, and fecal microbiota in weaned piglets.Journal of animal science · 2024Article
- Synbiotics improve growth performance and nutrient digestibility, inhibit PEDV infection, and prevent intestinal barrier dysfunction by mediating innate antivirus immune response in weaned piglets.Journal of animal science · 2024Article
- Benzoic acid supplementation improves the growth performance, nutrient digestibility and nitrogen metabolism of weaned lambs.Frontiers in veterinary science · 2024Article
- Effects of combined application of benzoic acid and 1-monolaurin on growth performance, nutrient digestibility, gut microbiome and inflammatory factor levels in weaned piglets.Porcine health management · 2023Article
- Research progress on anti-stress nutrition strategies in swine.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Review
- Comparative effects of benzoic acid and sodium benzoate in diets for nursery pigs on growth performance and acidification of digesta and urine.Journal of animal science · 2023Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs a organic acid, benzoic acid has become one of the most important alternatives for antibiotics, and its beneficial effect on performance in animals has been proven for a decade. However, knowledge of the effects of benzoic acid on jejunal digestive physiology, especially the antioxidant capacity and mucosal glucagon-like peptide 2 (GLP-2) concentrations is lacking.
methodsA total of 20 barrows [Duroc × (Yorkshire × Landrace)] with an average body weight (BW) of 18.75 ± 0.2 kg were used in a 14-d trial to determine the potential mechanisms of benzoic acid supplementation on the performance, nutrient digestibility and jejunal digestive physiology in young pigs. All pigs were randomly allotted to 1 of 2 diets supplemented with 0 or 5000 mg/kg benzoic acid.
resultsRelative to the control, benzoic acid supplementation increased the average daily feed intake (ADFI), and average daily gain (ADG) in young pigs (P < 0.05), improved the apparent total tract digestibility of dry matter (DM), crude protein (CP), ether extract (EE), gross energy (GE) and crude ash (P < 0.05), and enhanced the activities of trypsin, lipase and amylase in the jejunum (P < 0.05). Similarly, relative to the control, supplementing benzoic acid in the diet resulted in a trend to reduce the pH values of the digesta (P = 0.06), decreased crypt depth and increased the villus height to crypt depth ratio (P < 0.05) in the jejunum of pigs. Finally, benzoic acid supplementation increased the mRNA expression and concentration of glucagon-like peptide 2 and the activities of glutathione peroxidase and superoxide dismutase in the jejunal mucosa of young pigs (P < 0.05).
conclusionsIn conclusion, supplementation with 5000 mg/kg benzoic acid improved the performance of young pigs through promoting nutrient digestion, improving jejunal antioxidant capacity, and maintaining the jejunal morphology in young pigs.
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