Evidence map›Paper›PMID 27239299›Full record

ArticlePerioperative medicine (London, England)2016

Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients.

Sarka Moravcova, Bonnie Kyle, Hilary Shanahan, Savvas Giannaris, Andrew Smith, Colin Hamilton-Davies

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Perioperative medicine (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04430972 (Is Pre-operative Impaired imMune rEsponsiveness Associated With Adverse Outcome Following Aortic Valve Replacement SURgEry), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04430972 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Is Pre-operative Impaired imMune rEsponsiveness Associated With Adverse Outcome Following Aortic Valve Replacement SURgEry (MEASURE)

TypeobservationalSponsorBarts & The London NHS TrustRan2025 to 2026Enrolled150ConditionsAortic Valve Disease, Surgery--Complications, Immune System DisorderArmsAortic valve replacement
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sarka MoravcovaRoyal Brompton & Harefield NHS Trust, London, UK.
Bonnie KyleRoyal Brompton & Harefield NHS Trust, London, UK.
Hilary ShanahanBarts Health NHS Trust, London, UK.
Savvas GiannarisBarts Health NHS Trust, London, UK.
Andrew SmithBarts Health NHS Trust, London, UK.
Colin Hamilton-DaviesBarts Health NHS Trust, London, UK.
Barts Health NHS Trust · GBRoyal Brompton & Harefield NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery.

methodsWe examined the variability of anti-staphylococcal antibody levels across a group of healthy volunteers and compared this with patients scheduled to undergo cardiac surgery.

resultsPre-operative cardiac surgical patients exhibited significantly higher levels of staphylococcal antibodies compared with healthy volunteers.

conclusionsThe relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation.

Indexed as

AntibodyComplicationEndoCAbInfectionPre-operativeStaphylococcus

Identifiers

PMID27239299
PMCPMC4882792
OpenAlexW2403295513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.