ReviewInternational review of neurobiology2016
Modulation of BK Channel Function by Auxiliary Beta and Gamma Subunits.
Review in International review of neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
53 citing papers in PubMed, 91 citations in OpenAlex.
- Human Foetal Neuroblasts Exhibit BK Channel-Dependent Membrane Voltage Oscillations upon Depolarization.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Potassium channels in vascular smooth muscle cells.Physiological reviews · 2026Review
- Article
- LRRC55 modulates BK channels to support Purkinje cell plasticity and motor coordination.bioRxiv : the preprint server for biology · 2026Article
- Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- β2 and β3a regulatory subunits can coassemble in the same BK channels.The Journal of general physiology · 2026Article
- Smooth muscle of the lower urinary tract: BK-RyR coupling in physiology and pathophysiology.Journal of muscle research and cell motility · 2025Review
- Tuning the gate and the gear: The LRRC26 (bioRxiv : the preprint server for biology · 2025Article
- Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel.Nature communications · 2025Article
- Going with the flow: New insights regarding flow induced KPhysiological reports · 2024Review
- Transmembrane determinants of voltage-gating differences between BK (Slo1) and Slo3 channels.Biophysical journal · 2024Article
- Potentiation of BKCa channels by cystic fibrosis transmembrane conductance regulator correctors VX-445 and VX-121.The Journal of clinical investigation · 2024Article
- Gene expression, evolution, and the genetics of electrosensing in the smalltooth sawfish,Ecology and evolution · 2024Article
- Challenges in the Therapeutic Targeting of KCa Channels: From Basic Physiology to Clinical Applications.International journal of molecular sciences · 2024Review
- Large conductance voltage-and calcium-activated KFrontiers in pharmacology · 2024Review
- BK channels sustain neuronal CaCellular and molecular life sciences : CMLS · 2023Article
- BK channel modulation by positively charged peptides and auxiliary γ subunits mediated by the Ca2+-bowl site.The Journal of general physiology · 2023Article
- Regulation of Neurotransmitter Release by KAdvances in neurobiology · 2023Article
- Mapping the functional expression of auxiliary subunits of KScientific reports · 2022Article
- Novel Thioxothiazolo[3,4-ACS medicinal chemistry letters · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The large-conductance, Ca(2+)- and voltage-activated K(+) (BK) channel is ubiquitously expressed in mammalian tissues and displays diverse biophysical or pharmacological characteristics. This diversity is in part conferred by channel modulation with different regulatory auxiliary subunits. To date, two distinct classes of BK channel auxiliary subunits have been identified: β subunits and γ subunits. Modulation of BK channels by the four auxiliary β (β1-β4) subunits has been well established and intensively investigated over the past two decades. The auxiliary γ subunits, however, were identified only very recently, which adds a new dimension to BK channel regulation and improves our understanding of the physiological functions of BK channels in various tissues and cell types. This chapter will review the current understanding of BK channel modulation by auxiliary β and γ subunits, especially the latest findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.