ArticleHuman brain mapping2016
Acute white matter changes following sport-related concussion: A serial diffusion tensor and diffusion kurtosis tensor imaging study.
Article in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.
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Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Implications of DTI in mild traumatic brain injury for detecting neurological recovery and predicting long-term behavioural outcome in paediatric and young population-a systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Pooled it
- Characteristic patterns of white matter tract injury in sport-related concussion: An image based meta-analysis.NeuroImage. Clinical · 2020Pooled it
- The second decade of DTI in TBI part 1: a systematic review of mild TBI.Frontiers in neurologyPooled it
- Does timing matter? Unlocking the value of repeated MRI in the early phases after severe traumatic brain injury.Acta neurochirurgica · 2026Article
- Reduced cortical excitability is associated with head impact severity and cognitive symptoms in adolescent football players.iScience · 2026Article
- Linking a Deep Learning Model for Concussion Classification with Reorganization of Large-Scale Brain Networks in Female Youth.Bioengineering (Basel, Switzerland) · 2025Article
- Correlating Magnetoencephalography, Diffusion Kurtosis Imaging, Biomechanics, and Neuropsychology in American Youth Football.Journal of neurotrauma · 2025Article
- Clinical Assessment on Days 1-14 for the Characterization of Traumatic Brain Injury: Recommendations from the 2024 NINDS Traumatic Brain Injury Classification and Nomenclature Initiative Clinical/Symptoms Working Group.Journal of neurotrauma · 2025Review
- Sport-Related Concussions in High School Athletes: A Comprehensive Update.Current neurology and neuroscience reports · 2025Review
- Clinical utility of diffusion tensor imaging in sport-related concussion: a systematic review.BJR open · 2025Article
- A Comparative Neuroimaging Review of Repetitive Head Impacts and Mild Traumatic Brain Injury from Pediatrics to Professionals.Neurotrauma reports · 2025Review
- Reduced Cortical Excitability is Associated with Cognitive Symptoms in Concussed Adolescent Football Players.medRxiv : the preprint server for health sciences · 2024Article
- Differential neural mechanisms for movement adaptations following neuromuscular training in young female athletes with a history of sports-related concussion.Neuroscience · 2024Article
- Widespread White Matter Abnormalities in Concussed Athletes Detected by 7T Diffusion Magnetic Resonance Imaging.Journal of neurotrauma · 2024Article
- Review
- Review
- Longitudinal Biochemical and Behavioral Alterations in a Gyrencephalic Model of Blast-Related Mild Traumatic Brain Injury.Neurotrauma reports · 2024Article
- The effects of sports-related concussion history on female adolescent brain activity and connectivity for bilateral lower extremity knee motor control.Psychophysiology · 2023Article
- Microstructural Alterations in Tract Development in College Football and Volleyball Players: A Longitudinal Diffusion MRI Study.Neurology · 2023Article
- Comparison of Diagnostic Performance and Image Quality between Topup-Corrected and Standard Readout-Segmented Echo-Planar Diffusion-Weighted Imaging for Cholesteatoma Diagnostics.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Recent neuroimaging studies have suggested that following sport-related concussion (SRC) physiological brain alterations may persist after an athlete has shown full symptom recovery. Diffusion MRI is a versatile technique to study white matter injury following SRC, yet serial follow-up studies in the very acute stages following SRC utilizing a comprehensive set of diffusion metrics are lacking. The aim of the current study was to characterize white matter changes within 24 hours of concussion in a group of high school and collegiate athletes, using Diffusion Tensor and Diffusion Kurtosis Tensor metrics. Participants were reassessed a week later. At 24 hours post-injury, the concussed group reported significantly more concussion symptoms than a well-matched control group and demonstrated poorer performance on a cognitive screening measure, yet these differences were nonsignificant at the 8-day follow-up. Similarly, within 24-hours after injury, the concussed group exhibited a widespread decrease in mean diffusivity, increased axial kurtosis and, to a lesser extent, decreased axial and radial diffusivities compared with control subjects. At 8 days post injury, the differences in these diffusion metrics were even more widespread in the injured athletes, despite improvement of symptoms and cognitive performance. These MRI findings suggest that the athletes might not have reached full physiological recovery a week after the injury. These findings have significant implications for the management of SRC because allowing an athlete to return to play before the brain has fully recovered from injury may have negative consequences. Hum Brain Mapp 37:3821-3834, 2016. © 2016 Wiley Periodicals, Inc.
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