Evidence map›Paper›PMID 27236815›Full record

ArticleEuropean radiology2017

Quantitative ultrasound mapping of regional variations in shear wave speeds of the aging Achilles tendon.

Laura Chernak Slane, Jack Martin, Ryan DeWall, Darryl Thelen, Kenneth Lee

Abstract read
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Objective Assessment of Regional Stiffness in Achilles Tendon in Different Ankle Joint Positions Using the MyotonPRO.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Trial
  3. Achilles Tendon Shear Wave Velocity Within a 1-Year Follow-Up After Non-Operatively Treated Rupture.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  4. Article
  5. Observational
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Article
  11. Aging and injury affect nuclear shape heterogeneity in tendon.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Tensile mechanical changes in the Achilles tendon due to Insertional Achilles tendinopathy.Journal of the mechanical behavior of biomedical materials · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Laura Chernak SlaneDepartment of Radiology, 600 Highland Avenue, University of Wisconsin-Madison, Madison, WI, USA. laura.c.slane@gmail.com.
Jack MartinMaterials Science Program, 1415 Engineering Drive, University of Wisconsin-Madison, Madison, WI, USA.
Ryan DeWallDepartment of Radiology, 600 Highland Avenue, University of Wisconsin-Madison, Madison, WI, USA.
Darryl ThelenMaterials Science Program, 1415 Engineering Drive, University of Wisconsin-Madison, Madison, WI, USA.
Kenneth LeeDepartment of Radiology, 600 Highland Avenue, University of Wisconsin-Madison, Madison, WI, USA.
University of Wisconsin–Madison · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
NCATS NIH HHS UL1 TR000427NCRR NIH HHS UL1 RR025011
6 · The paper itself

Abstract

objectivesEvaluate the effects of aging on healthy Achilles tendon and aponeurosis shear wave speed (SWS), a quantitative metric which reflects tissue elasticity.

methodsShear wave elastography was used to measure spatial variations in Achilles tendon SWS in healthy young (n = 15, 25 ± 4 years), middle-aged (n = 10, 49 ± 4 years) and older (n = 10, 68 ± 5 years) adults. SWS was separately measured in the free Achilles tendon, soleus aponeurosis and gastrocnemius aponeurosis in resting (R), stretched (dorsiflexed 15° from R) and slack (plantarflexed 15° from R) postures.

resultsSWS significantly increased with stretch and varied with age in all tendon regions. Slack free tendon SWS was significantly higher in older adults than young adults (p = 0.025). However, stretched soleus aponeurosis SWS was significantly lower in older adults than young adults (p = 0.01). Stretched gastrocnemius aponeurosis SWS was significantly lower in both middle-aged (p = 0.003) and older (p = 0.001) adults, relative to younger adults.

conclusionThese results suggest that aging alters spatial variations in Achilles tendon elasticity, which could alter deformations within the triceps surae muscle-tendon units, thus affecting injury potential. The observed location- and posture-dependent variations highlight the importance of controlling ankle posture and imaging location when using shear wave approaches clinically to evaluate tendon disorders. KEY POINTS: • Shear wave elastography shows promise as a clinical quantitative ultrasound-based technique. • Aging induces location-dependent changes in Achilles tendon shear wave speed. • Spatial and postural dependence necessitates careful integration of this approach clinically.

Indexed as

Achilles TendonAdultAgedAgingAnkle JointElasticityElasticity Imaging TechniquesFemaleHumansMaleMiddle AgedMuscle, SkeletalUltrasonographyYoung AdultAgingComplianceElastographyTendonUltrasound

Identifiers

PMID27236815
PMCPMC5125901
OpenAlexW2395486108

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.