ReviewTrends in parasitology2016
Grandeur Alliances: Symbiont Metabolic Integration and Obligate Arthropod Hematophagy.
Review in Trends in parasitology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed.
- Laboratory evolution drives continued genome degradation in the facultative tsetse symbiont Sodalis glossinidius.PLoS neglected tropical diseases · 2026Article
- Friends or foes: Unraveling the tsetse fly-Spiroplasma symbiosis.PLoS neglected tropical diseases · 2026Review
- Article
- Allergic reactions associated with tsetse fly bites.Annals of medicine · 2025Article
- Differentiation in bacterial symbiont growth between insecticide treated and untreated tropical bed bug.Antonie van Leeuwenhoek · 2025Article
- Shrinking in the dark: Parallel endosymbiont genome erosions are associated with repeated host transitions to an underground life.Insect science · 2024Article
- Metagenome reveals the midgut microbial community of Haemaphysalis qinghaiensis ticks collected from yaks and Tibetan sheep.Parasites & vectors · 2024Article
- Article
- Insect-microbe interactions and their influence on organisms and ecosystems.Ecology and evolution · 2024Review
- Article
- Ticks without borders: microbiome of immature neotropical tick species parasitizing migratory songbirds along northern Gulf of Mexico.Frontiers in cellular and infection microbiology · 2024Article
- Microbiota profile in organs of the horseflies (Diptera: Tabanidae) in Northeastern China.Frontiers in microbiology · 2024Article
- Development, feeding, and sex shape the relative quantity of the nutritional obligatory symbiontFrontiers in microbiology · 2024Article
- Differential associations of horizontally and vertically transmitted symbionts on Ixodes ricinus behaviour and physiology.Parasites & vectors · 2023Article
- Adenosine triphosphate overrides the aversive effect of antifeedants and toxicants: a model alternative phagostimulant for sugar-based vector control tools.Parasites & vectors · 2023Article
- Impact of the microbiome on mosquito-borne diseases.Protein & cell · 2023Review
- Three-dimensional images reveal the impact of the endosymbiont Midichloria mitochondrii on the host mitochondria.Nature communications · 2023Article
- Metagenomics of culture isolates and insect tissue illuminate the evolution ofMicrobial genomics · 2023Article
- Decontamination protocols affect the internal microbiota of ticks.Parasites & vectors · 2023Article
- Entomopathogenic fungus treatment changes the gut bacterial diversity of Rhipicephalus microplus ticks.Parasites & vectors · 2023Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Several arthropod taxa live exclusively on vertebrate blood. This food source lacks essential metabolites required for the maintenance of metabolic homeostasis, and as such, these arthropods have formed symbioses with nutrient-supplementing microbes that facilitate their host's 'hematophagous' feeding ecology. Herein we highlight metabolic contributions of bacterial symbionts that reside within tsetse flies, bed bugs, lice, reduviid bugs, and ticks, with specific emphasis on B vitamin and cofactor biosynthesis. Importantly, these arthropods can transmit pathogens of medical and veterinary relevance and/or cause infestations that induce psychological and dermatological distress. Microbial metabolites, and the biochemical pathways that generate them, can serve as specific targets of novel control mechanisms aimed at disrupting the metabolism of hematophagous arthropods, thus combatting pest invasion and vector-borne pathogen transmission.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.