Evidence map›Paper›PMID 27236540›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2016

Preoperative haemoglobin cut-off values for the prediction of post-operative transfusion in total knee arthroplasty.

Jared Ze Yang Yeh, Jerry Yongqiang Chen, Hamid Rahmatullah Bin Abd Razak, Bryan Huai Gu Loh, Ying Hao, Andy Khye Soon Yew, Shi-Lu Chia, Ngai Nung Lo, Seng Jin Yeo

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

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16citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  15. What Should Define Preoperative Anemia in Primary THA?Clinical orthopaedics and related research · 2017
    Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jared Ze Yang YehDuke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. jared.yeh.zy@gmail.com.
Jerry Yongqiang ChenDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Hamid Rahmatullah Bin Abd RazakDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Bryan Huai Gu LohDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Ying HaoDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Andy Khye Soon YewDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Shi-Lu ChiaDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Ngai Nung LoDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Seng Jin YeoDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to determine preoperative haemoglobin cut-off values that could accurately predict post-operative transfusion outcome in patients undergoing primary unilateral total knee arthroplasty (TKA). This will allow surgeons to provide selective preoperative type and screen to only patients at high risk of transfusion.

methodsA total of 1457 patients diagnosed with osteoarthritis and underwent primary unilateral TKA between January 2012 and December 2014 were retrospectively reviewed. Logistic regression analyses were applied to identify factors that could predict transfusion outcome.

resultsA total of 37 patients (2.5 %) were transfused postoperatively. Univariate analysis revealed preoperative haemoglobin (p < 0.001), age (p < 0.001), preoperative haematocrit (p < 0.001), and preoperative creatinine (p < 0.001) to be significant predictors. In the multivariate analysis with patients dichotomised at 70 years of age, preoperative haemoglobin remained significant with adjusted odds ratio of 0.33. Receiver operating characteristic curve identified the preoperative haemoglobin cut-off values to be 12.4 g/dL (AUC = 0.86, sensitivity = 87.5 %, specificity = 77.2 %) and 12.1 g/dL (AUC = 0.85, sensitivity = 69.2 %, specificity = 87.1 %) for age above and below 70, respectively.

conclusionsThe authors recommend preoperative haemoglobin cut-off values of 12.4 g/dL for age above 70 and 12.1 g/dL for age below 70 to be used to predict post-operative transfusion requirements in TKA. To maximise the utilisation of blood resources, the authors recommend that only patients with haemoglobin level below the cut-off should receive routine preoperative type and screen before TKA. LEVEL OF EVIDENCE: IV.

Indexed as

Blood Loss, SurgicalBlood TransfusionPostoperative CareAgedArthroplasty, Replacement, KneeCreatinineFemaleHematocritHemoglobinsHumansMaleMultivariate AnalysisOdds RatioOsteoarthritis, KneeRetrospective StudiesROC CurveCreatinineHemoglobinsHaemoglobinKnee replacementPreoperativeTotal knee arthroplastyTransfusion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.