Evidence map›Paper›PMID 27236387›Full record

SynthesisAnnals of Saudi medicine

Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis.

Lin Liang, Xinlei Chen, Weimin Jiang, Xuefeng Li, Jie Chen, Lijun Wu, Yangyi Zhu

Open access · diamondAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Sphereplasty with 3D porous titanium microspheres for thoracolumbar vertebral compression fractures: analysis of clinical efficacy and safety profile of a novel technique.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Effect of different cement distribution on the clinical efficacy of vertebral compression fractures in unilateral percutaneous vertebroplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Review
  5. Article
  6. Article
  7. Comparison of the efficacy and safety of vertebroplasty with different pedicle approaches for osteoporotic vertebral.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. [Epidemiological and clinical characteristics analysis of 681 cases of thoracolumbar osteoporotic vertebral compression fractures].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2022
    Article
  13. Review
  14. Article
  15. Article
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  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Lin Liang
Xinlei Chen
Weimin Jiang
Xuefeng Li
Jie Chen
Lijun Wu
Yangyi ZhuProf. Yangyi Zhu, Department of Orthopaedics,, Shangyu People's Hospital, University,, No. 899 Pinghai Road, Suzhou 215006, China, Shaoxing 312000, China, F: 86057581266120, boss2014jaing@163.com, ORCID ID: orcid.org/0000-0002-2654-8360.
First Affiliated Hospital of Soochow University · CNAffiliated Hospital of Nantong University · CNShangluo Central Hospital · CNShaoxing No.6 People's Hospital · CNShaoxing People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth kyphoplasty (KP) and vertebroplasty (VP) are effective for patients with osteoporotic vertebral compression fracture (OVCF), but which approach might be more effective remains unclear, so we decided to update earlier systematic reviews.

objectiveReview and analyze studies published as of August 2015 that compared clinical outcomes and complications of KP versus VP.

designSystematic review and meta-analysis. SEARCH

methodPublished reports up to August 2015 were found in PubMed, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL). SELECTION CRITERIA: Randomized controlled trials (RCTs) and prospective and retrospective cohort stud.ies comparing KP and VP in patients with OVCF. DATA COLLECTION AND ANALYSIS: Two authors independently assessed the studies and extracted data.

resultsThirty-two studies involving 3274 patients fulfilled the inclusion criteria. There were significant differences between the two groups in short- and long-term postoperative changes in measures of pain intensity and dysfunction (P < .01), in anterior and middle height (P < .01), kyphotic angle (P < .01), and time to injury, but not in posterior height (P=.178). There were no significant differences in the rate of postoperative fractures including adjacent and total fractures, but cement leakage to the intraspinal space was greater in the VP group (P=.035). KP surgery took longer and required a greater volume of injected cement.

conclusionsKR resulted in better pain relief, improvements in Oswestry dysfunction and radiographic outcomes with less cement leakage, but further RCTs are needed to verify this conclusion. LIMITATIONS: Only four RCTs with a certain of risk of bias. Most studies were observational.

Indexed as

Bone CementsDisability EvaluationFractures, CompressionHumansKyphoplastyOperative TimeOsteoporotic FracturesPain MeasurementSpinal FracturesTreatment OutcomeVertebroplastyBone Cements

Identifiers

PMID27236387
PMCPMC6074542
OpenAlexW2413566620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.