Evidence map›Paper›PMID 27235304›Full record

ArticleBMJ open2016

Non-specific mechanisms in orthodox and CAM management of low back pain (MOCAM): theoretical framework and protocol for a prospective cohort study.

Katherine Bradbury, Miznah Al-Abbadey, Dawn Carnes, Borislav D Dimitrov, Susan Eardley, Carol Fawkes, Jo Foster, Maddy Greville-Harris, J Matthew Harvey, Janine Leach and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Katherine BradburyDepartment of Psychology, University of Southampton, Southampton, UK.
Miznah Al-AbbadeyDepartment of Psychology, University of Southampton, Southampton, UK.
Dawn CarnesBlizard Institute, Queen Mary University of London, London, UK.
Borislav D DimitrovPrimary Care and Population Sciences, University of Southampton, Southampton, UK.
Susan EardleyPrimary Care and Population Sciences, University of Southampton, Southampton, UK.
Carol FawkesBlizard Institute, Queen Mary University of London, London, UK.
Jo FosterDepartment of Psychology, University of Southampton, Southampton, UK.
Maddy Greville-HarrisDepartment of Psychology, University of Southampton, Southampton, UK.
J Matthew HarveyDepartment of Psychology, University of Southampton, Southampton, UK.
Janine LeachClinical Research Centre for Health Professions, University of Brighton, Brighton, UK.
George LewithPrimary Care and Population Sciences, University of Southampton, Southampton, UK.
Hugh MacPhersonHealth Sciences, University of York, New York, UK.ORCID 0000-0003-4255-4768
Lisa RobertsHealth Sciences, University of Southampton, Southampton, UK.
Laura ParryDepartment of Psychology, University of Southampton, Southampton, UK.
Lucy YardleyDepartment of Psychology, University of Southampton, Southampton, UK.
Felicity L BishopDepartment of Psychology, University of Southampton, Southampton, UK.
University of Southampton · GBQueen Mary University of London · GBUniversity of Brighton · GBUniversity of York · GB

Funding

Arthritis Research UK 20552
6 · The paper itself

Abstract

introductionComponents other than the active ingredients of treatment can have substantial effects on pain and disability. Such 'non-specific' components include: the therapeutic relationship, the healthcare environment, incidental treatment characteristics, patients' beliefs and practitioners' beliefs. This study aims to: identify the most powerful non-specific treatment components for low back pain (LBP), compare their effects on patient outcomes across orthodox (physiotherapy) and complementary (osteopathy, acupuncture) therapies, test which theoretically derived mechanistic pathways explain the effects of non-specific components and identify similarities and differences between the therapies on patient-practitioner interactions. METHODS AND ANALYSIS: This research comprises a prospective questionnaire-based cohort study with a nested mixed-methods study. A minimum of 144 practitioners will be recruited from public and private sector settings (48 physiotherapists, 48 osteopaths and 48 acupuncturists). Practitioners are asked to recruit 10-30 patients each, by handing out invitation packs to adult patients presenting with a new episode of LBP. The planned multilevel analysis requires a final sample size of 690 patients to detect correlations between predictors, hypothesised mediators and the primary outcome (self-reported back-related disability on the Roland-Morris Disability Questionnaire). Practitioners and patients complete questionnaires measuring non-specific treatment components, mediators and outcomes at: baseline (time 1: after the first consultation for a new episode of LBP), during treatment (time 2: 2 weeks post-baseline) and short-term outcome (time 3: 3 months post-baseline). A randomly selected subsample of participants in the questionnaire study will be invited to take part in a nested mixed-methods study of patient-practitioner interactions. In the nested study, 63 consultations (21/therapy) will be audio-recorded and analysed quantitatively and qualitatively, to identify communication practices associated with patient outcomes. ETHICS AND DISSEMINATION: The protocol is approved by the host institution's ethics committee and the NHS Health Research Authority Research Ethics Committee. Results will be disseminated via peer-reviewed journal articles, conferences and a stakeholder workshop.

Indexed as

AcupunctureOsteopathic MedicinePhysical Therapy ModalitiesAttitude of Health PersonnelDisability EvaluationHealth Facility EnvironmentHealth Knowledge, Attitudes, PracticeHumansLow Back PainPain ManagementPhysician-Patient RelationsProspective StudiesResearch DesignTreatment OutcomeCOMPLEMENTARY MEDICINEPAIN MANAGEMENTPRIMARY CARERHEUMATOLOGY

Identifiers

PMID27235304
PMCPMC4885467
OpenAlexW2396978341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.